58255-18-8 Usage
Uses
Given the nature of the provided materials, the primary use of N-Methyl-(2-thienylmethyl)amine, or methiopropamine, is illicit and not recommended for any legal or safe application. However, for the sake of providing a comprehensive overview, the substance has been known to be used as a stimulant and psychoactive agent in some cases of drug abuse. It is important to emphasize that the use of methiopropamine is dangerous and illegal in many jurisdictions due to its potential for causing harm and its classification as a controlled substance.
Used in Illicit Drug Use:
N-Methyl-(2-thienylmethyl)amine is used as a stimulant and psychoactive agent for its effects similar to amphetamines, despite being associated with drug overdose and abuse, and being a controlled substance in many countries.
Check Digit Verification of cas no
The CAS Registry Mumber 58255-18-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,2,5 and 5 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 58255-18:
(7*5)+(6*8)+(5*2)+(4*5)+(3*5)+(2*1)+(1*8)=138
138 % 10 = 8
So 58255-18-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H9NS/c1-7-5-6-3-2-4-8-6/h2-4,7H,5H2,1H3/p+1
58255-18-8Relevant academic research and scientific papers
Selective Monomethylation of Amines with Methanol as the C1 Source
Choi, Geunho,Hong, Soon Hyeok
supporting information, p. 6166 - 6170 (2018/04/30)
The N-monomethyl functionality is a common motif in a variety of synthetic and natural compounds. However, facile access to such compounds remains a fundamental challenge in organic synthesis owing to selectivity issues caused by overmethylation. To address this issue, we have developed a method for the selective, catalytic monomethylation of various structurally and functionally diverse amines, including typically problematic primary aliphatic amines, using methanol as the methylating agent, which is a sustainable chemical feedstock. Kinetic control of the aliphatic amine monomethylation was achieved by using a readily available ruthenium catalyst at an adequate temperature under hydrogen pressure. Various substrates including bio-related molecules and pharmaceuticals were selectively monomethylated, demonstrating the general utility of the developed method.
