58255-18-8 Usage
General Description
N-Methyl-(2-thienylmethyl)amine, also known as methiopropamine, is a synthetic amine compound with a molecular formula of C8H11N. It is derived from thienylmethylamine and has a methyl group attached to the amine nitrogen. Methiopropamine is classified as a designer drug and is structurally similar to methamphetamine, but with a thiophene ring in place of the phenyl group. It has stimulant and psychoactive properties, with effects similar to those of amphetamines. Methiopropamine has been implicated in numerous cases of drug overdose and abuse, and its use is associated with potential health risks. It is considered a controlled substance in many countries and its use is regulated.
Check Digit Verification of cas no
The CAS Registry Mumber 58255-18-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,2,5 and 5 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 58255-18:
(7*5)+(6*8)+(5*2)+(4*5)+(3*5)+(2*1)+(1*8)=138
138 % 10 = 8
So 58255-18-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H9NS/c1-7-5-6-3-2-4-8-6/h2-4,7H,5H2,1H3/p+1
58255-18-8Relevant articles and documents
Selective Monomethylation of Amines with Methanol as the C1 Source
Choi, Geunho,Hong, Soon Hyeok
supporting information, p. 6166 - 6170 (2018/04/30)
The N-monomethyl functionality is a common motif in a variety of synthetic and natural compounds. However, facile access to such compounds remains a fundamental challenge in organic synthesis owing to selectivity issues caused by overmethylation. To address this issue, we have developed a method for the selective, catalytic monomethylation of various structurally and functionally diverse amines, including typically problematic primary aliphatic amines, using methanol as the methylating agent, which is a sustainable chemical feedstock. Kinetic control of the aliphatic amine monomethylation was achieved by using a readily available ruthenium catalyst at an adequate temperature under hydrogen pressure. Various substrates including bio-related molecules and pharmaceuticals were selectively monomethylated, demonstrating the general utility of the developed method.