58341-56-3Relevant academic research and scientific papers
Synthesis and conformational analysis of substituted 2,6-dioxabicycloheptanes: 1,3-anhydro-2,4-di-O-benzyl-6-deoxy-β-D-glucopyranose by 1H-NMR spectroscopy and molecular mechanics calculation
Wu, Xinfu,Kong, Fanzuo,Lu, Depei,Zhang, Pang
, p. 75 - 88 (1992)
A highly selective ring opening reduction of methyl 3-O-allyl-2-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside provided the 2,4-di-O-benzyl derivative.This was toluenesulfonylated or iodinated and subsequently reduced to give crystalline methyl 3-O-allyl-
Design and synthesis of a trisubstrate analogue for α(1 →3)fucosyltransferase: A potential inhibitor
Heskamp,Veeneman,Van Der Marel,Van Boeckel,Van Boom
, p. 8397 - 8406 (2007/10/02)
Phenyl 1-azido-3,4,5-tri-O-benzyl-I-deoxy-2-seleno-α-1-fuco-heptulopyranoside (5), readily accessible from perbenzylated 1-fucono-1,5-lactone, is a key intermediate in the preparation of trisubstrate analogue 2. NIS mediated condensation of fucosyl donor 5 with methyl 2,4,6-tri-O-benzyl-α-d-glucopyranoside (7) and ensuing reduction of the azido function furnished ketodisaccharide 10b, which was elongated at the 1-amino group of the fucose residue with a malonic acid spacer. The thus obtained compound was deprotected and subsequently coupled with 5′-amino-5′-deoxy-guanosine to afford the target compound 2.
Substrates for the differentiation of the N-acetylglucosaminyltransferases. Synthesis of βDGlcNAc(->2)αDMan(1->6)βDMan and βDGlcNAc(1->2)αDMan(1->6)3)βDMan glycosides
Tahir, S. Hasan,Hindsgaul, Ole
, p. 1771 - 1780 (2007/10/02)
The trisaccharide βDGlcNAc(1->2)αDMan(1->6)βDMan (2) and the tetrasaccharide βDGlcNAc(1->2)αDMan(1->6)αDMan(1->3)>βDMan (3) have been chemically synthesized as their 8-methoxycarbonyloctyl glycosides.Compounds 2 and 3, both partial structures of naturally
