58358-37-5

Basic information

• Product Name: Benzeneacetic acid, 2,5-diMethyl-, ethyl ester
• Synonyms: Benzeneacetic acid, 2,5-diMethyl-, ethyl ester;(2,5-Dimethylphenyl)acetic acid ethyl ester
• CAS NO: 58358-37-5
• Molecular Formula: C₁₂H₁₆O₂
• Molecular Weight: 192.25424
• Mol File: 58358-37-5.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzeneacetic acid, 2,5-diMethyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, 2,5-diMethyl-, ethyl ester(58358-37-5)
• EPA Substance Registry System: Benzeneacetic acid, 2,5-diMethyl-, ethyl ester(58358-37-5)

Safety Data

• Hazardous Substances Data: 58358-37-5(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 64-17-5 ethanol 
• 22328-43-4 2,5-dimethylbenzoyl chloride 
• 55312-97-5 2-(2,5-dimethylphenyl)acetyl chloride 
• 589-18-4 4-Methylbenzyl alcohol 
• 623-73-4 diazoacetic acid ethyl ester 
• 106-42-3 para-xylene 
• 53957-33-8 2,5-dimethylbenzyl alcohol 
• 95-92-1 oxalic acid diethyl ester 
• 13612-34-5 2-(2,5-dimethylphenyl)acetic acid 
• 610-72-0 2,5-dimethylbenzoic acid 
• 95-78-3 2,5-Dimethylaniline 
• 553-94-6 4-bromo-m-xylene 
• 824-45-3 2,5-dimethylbenzyl chloride 

Downstream Products

• 13612-34-5 2-(2,5-dimethylphenyl)acetic acid 
• 28081-38-1 2-(2',5'-dimethylphenyl)ethyl bromide 
• 53806-66-9 diethyl 2,5-dimethyl-1,4-benzenediacetate 
• 105077-02-9 diethyl α-methylthio-2,5-dimethyl-1,4-benzenediacetate 
• 83026-40-8 diethyl (2,5-dimethylphenyl)propanedioate 
• 6972-51-6 2-(2,5-dimethylphenyl)ethan-1-ol 

Relevant articles and documents

Synthesis method and application of 1, 3-bis(2, 5-dimethylphenyl)propan-2-one

The invention discloses a synthesis method of 1, 3-bis(2, 5-dimethylphenyl)propan-2-one. The method includes: taking 2, 5-dimethylphenylacetic acid as the raw material, carrying out acylation and ethyl esterification reaction to obtain the intermediate et

Iron and manganese catalysts for the selective functionalization of arene C(sp2)-H bonds by carbene insertion

The first examples of the direct functionalization of non-activated aryl sp2 C-H bonds with ethyl diazoacetate (N2CHCO2Et) catalyzed by Mn- or Fe-based complexes in a completely selective manner are reported, with no formation of the frequently observed cycloheptatriene derivatives through competing Buchner reaction. The best catalysts are FeII or MnII complexes bearing the tetradentate pytacn ligand (pytacn= 1-(2-pyridylmethyl)-4,7-dimethyl-1,4,7-triazacyclononane). When using alkylbenzenes, the alkylic C(sp3)-H bonds of the substituents remained unmodified, thus the reaction being also selective toward functionalization of sp2 C-H bonds. Exclusive catalysis: Iron- and-manganese-based catalysts selectively functionalize the C(sp2)-H bonds of benzene or alkylbenzenes through the formal insertion of the CHCO2Et group from N2CHCO2Et (see scheme). When using alkylbenzenes, the alkylic C(sp3)-H bonds of the substituents remain unmodified.

AMINO ACID DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS

There is provided compounds of formula I, wherein R 1, R 2, R 3, R x, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required as in thrombosis or as anticoagulants.