58367-63-8Relevant academic research and scientific papers
Copper-catalyzed amination of silyl ketene acetals with N-chloroamines
Miura, Tomoya,Morimoto, Masao,Murakami, Masahiro
supporting information, p. 5214 - 5217,4 (2020/09/02)
A copper(I)/2,2′-bipyridyl complex catalyzes an amination reaction of silyl ketene acetals with N-chloroamines, presenting a new preparative method of α-amino esters.
Stereochemistry of Silyl Ketene Acetals of Some 8-Phenylmenthyl Arylacetates
Solladie-Cavallo, Arlette,Csaky, Aurelio G.
, p. 2585 - 2589 (2007/10/02)
Trimethylsilyl ketene acetals derived from 8-phenylmenthyl phenyl-, p-fluorophenyl, and p-(trifluoromethyl)phenylacetates, methyl phenylacetate, and isopropyl phenylacetate have been studied.It was shown that it is not possible, under kinetic conditions, to form exclusively the desired E-isomer and that the thermodynamic Z-isomer is also obtained as the major product under reaction conditions which can be considered kinetic.The results could be rationalized using the Ireland's and Dauben's models on the basis of the changes in the acidity of the proton to be abstraced and the strength of the base.Dimethyl-tert-butylsilyl ketene acetals have been studied.It appeared that reaction of TBDMSCl onto the Li-enolates favored the E-isomer.We proposed that, at the temperature (above -20 deg C) at which the reaction occurs, the E-Z equilibrium between the Li-enolates starts to play a role, and therefore the silyl ketene acetals E/Z ratios are kinetically controlled but by the second step (reaction of the reagent onto the Li-enolate).
REGIOSPECIFIC ORTHO OXYFUNCTIONALIZATION OF SUBSTITUTED BENZENES WITH SINGLET OXYGEN
Saito, Isao,Nagata, Ryu,Kotsuki, Hiyoshizo,Matsuura, Teruo
, p. 1717 - 1720 (2007/10/02)
A new procedure for regiospecific ortho oxyfunctionalization of phenylacetones, phenylacetic acid esters and phenylacetaldehyde has been developed.The method involves tert-butyldimethylsilylation, singlet oxygenation and successive reduction.
