58373-59-4

Usage

Uses

Used in Pharmaceutical Industry:
N-(2,4-Dichlorophenyl)benzenamine is used as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Dye Industry:
N-(2,4-Dichlorophenyl)benzenamine is utilized as a precursor in the production of dyes, playing a significant role in the creation of colorants for various applications.
Used in Pesticide and Herbicide Manufacturing:
N-(2,4-Dichlorophenyl)benzenamine is employed as a vital component in the manufacturing process of pesticides and herbicides, enhancing their effectiveness in controlling pests and unwanted plant growth.
Used in Organic Compound Synthesis:
As an aromatic amine, it is used as a building block in the synthesis of a wide range of organic compounds, contributing to the advancement of organic chemistry and the development of new materials and products.

Upstream product

• 18201-58-6 N-(2,4-dichloro-phenyl)-anthranilic acid 
• 13246-96-3 2,4-Dichlorophenoxyacetanilide 
• 626239-02-9 2-Chloro-N-(2,4-dichloro-phenyl)-N-phenyl-acetamide 
• 554-00-7 2,4-Dichloroaniline 
• 118-91-2 ortho-chlorobenzoic acid 
• 98-80-6 phenylboronic acid 
• 639-58-7 triphenyltin chloride 
• 2592-95-2 benzotriazol-1-ol 
• 626239-03-0 N-(2,4-dichloro-phenyl)-2-hydroxy-N-phenyl-acetamide 

Downstream Products

• 70172-31-5 diclofenac 
• 626239-03-0 N-(2,4-dichloro-phenyl)-2-hydroxy-N-phenyl-acetamide 
• 13246-96-3 2,4-Dichlorophenoxyacetanilide 
• 575-90-6 2,6-dichlorophenoxyacetic acid 

Relevant academic research and scientific papers

Peptide Nanofiber Templated Zinc Oxide Nanostructures as Non-precious Metal Catalyzed N-Arylation of Amines, One-Pot Synthesis of ImidazoHeterocycles and Fused Quinazolines

In the present study, peptide nanofiber was used to immobilize zinc oxide. This nanoparticle was prepared through self-assembly in an aqueous solution. The structural properties of the prepared catalyst were examined by a series of techniques, such as FT-IR, EDS, SEM, TEM, XRD, ICP-OES (inductively coupled plasma optical emission spectrometry), and ultraviolet–visible (UV–Vis) spectroscopy. TEM images showed the necklace model for peptide nanofiber decorated with zinc oxide. The versatility of the method was investigated by N-arylation using reaction of amines with hydroxybenzotriazole as a novel phenylating reagent, one-pot synthesis of imidazoheterocycles by a three-component reaction of 2-aminopyridine, aldehyde, terminal alkyne and preparation of tetracyclic quinazolinone ring by one-pot reaction of isatoic anhydride, amine, and ninhydrin. High yields, low cost of catalyst, environmental friendliness, efficient recovery and recyclability of catalyst are the most important features of this catalytic system.

Triphenyltin chloride as a new source of phenyl group for C-heteroatom and C-C bond formation

Ph3SnCl is introduced as a very suitable source of phenyl group for coupling with phenols, amines, and thiols in the presence of Cu(OAc)2 in Et3N at room temperature to give aryl ethers, amines, and arylthio ethers in high yields. In addition, the application of Ph3SnCl in the Stille coupling of aryl halides in the presence of Pd(0) catalyst in PEG 400 at 110C is discussed.

Practical copper-catalyzed N-arylation of amines with 20% aqueous solution of n-Bu4NOH

N-Arylation of a wide variety of amines with phenylboronic acid catalyzed by copper acetate under 20% aqueous solution of n-Bu4NOH was accomplished in good to excellent yields (up to 92%) and substrate conversions (up to 96%).

A convenient preparation of N-alkyl and N-arylamines by smiles rearrangement - Synthesis of analogues of diclofenac

Smiles rearrangement of substituted aryloxyacetamides in which oxygen and nitrogen are separated by COCH2 group has been successful even when the aryloxy ring carries weak or no electron withdrawing group. Earlier reports of such reactions involved either strong electron withdrawing groups or a special catalyst. The diphenylamines thus obtained gave analogues of diclofenac in only one case.