58379-82-1 Usage
General Description
1-N-PROPYL-1-TOSYLMETHYL ISOCYANIDE, also known as PPTMIC, is a chemical compound with the formula C11H15NO. It is a tosylmethyl isocyanide derivative that is commonly used in organic synthesis as a reagent for the synthesis of various organic compounds. PPTMIC is known for its ability to participate in a wide range of chemical reactions, making it valuable in the field of organic chemistry. Its unique structure and reactivity make it a versatile tool for the preparation of diverse molecules, and it has found applications in the development of pharmaceuticals and other fine chemicals. Despite its potential usefulness, PPTMIC should be handled with care due to its toxicity and potential health hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 58379-82-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,3,7 and 9 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 58379-82:
(7*5)+(6*8)+(5*3)+(4*7)+(3*9)+(2*8)+(1*2)=171
171 % 10 = 1
So 58379-82-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H15NO2S/c1-4-5-12(13-3)16(14,15)11-8-6-10(2)7-9-11/h6-9,12H,4-5H2,1-2H3
58379-82-1Relevant articles and documents
TosMIC and its derivatives as versatile sulfonylating agents for the synthesis of p-toluenesulfonylarenes from aryl halides and arylboronic acids
Ravi Kumar,Ramesh,Banik, Swarnayu,Subba Reddy
, (2020/11/02)
An efficient copper(II) catalyzed sulfonyation of aryl halides has been achieved using TosMIC (p-toluenesulfonylmethyl isocyanide) as a sulfonylating agent. This newly developed sulfonylation approach provides an easy access for the synthesis of diaryl sulfones from aryl bromides, iodides and boronic acids with TosMIC under neutral conditions. This method is useful for the sulfonylation of aryl boronic acids under similar conditions. This is the first report on the sulfonylation of aryl bromides, iodides and boronic acids using TosMIC.