583829-87-2Relevant academic research and scientific papers
Synthesis and properties of 2′-O,4′-C-methyleneoxymethylene bridged nucleic acid
Hari, Yoshiyuki,Obika, Satoshi,Ohnishi, Ryo,Eguchi, Ken,Osaki, Tomohisa,Ohishi, Hirofumi,Imanishi, Takeshi
, p. 1029 - 1038 (2007/10/03)
A novel bridged nucleic acid (BNA) analogue, 2′-O,4′-C- methyleneoxymethylene bridged nucleic acid (2′,4′-BNA COC), was synthesized and incorporated into oligonucleotides. The 2′,4′-BNACOC modified oligonucleotides showed high bindin
