583829-90-7Relevant academic research and scientific papers
Synthesis and properties of 2′-O,4′-C-methyleneoxymethylene bridged nucleic acid
Hari, Yoshiyuki,Obika, Satoshi,Ohnishi, Ryo,Eguchi, Ken,Osaki, Tomohisa,Ohishi, Hirofumi,Imanishi, Takeshi
, p. 1029 - 1038 (2007/10/03)
A novel bridged nucleic acid (BNA) analogue, 2′-O,4′-C- methyleneoxymethylene bridged nucleic acid (2′,4′-BNA COC), was synthesized and incorporated into oligonucleotides. The 2′,4′-BNACOC modified oligonucleotides showed high bindin
NUCLEOSIDE ANALOGUES AND OLIGONUCLEOTIDE DERIVATIVE COMPRISING NUCLEOTIDE ANALOGUE THEREOF
-
Page 20-21, (2008/06/13)
Compounds of the following general formula (1) and salts thereof: where A represents a direct bond, an alkylene group having 1 to 4 carbon atoms, etc.; B represents an aromatic heterocyclic group which may have a substituent, etc.; R1, R2
