583829-86-1

Upstream product

• 108-24-7 acetic anhydride 
• 212970-72-4 {3-[(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)methyl]-(1S,3R,4S,5R)-7,7-dimethyl-2,6,8-trioxa-4-(phenylmethoxy)bicyclo[3.3.0]oct-3-yl}methan-1-ol 

Downstream Products

• 877823-49-9 4-N-benzoyl-3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-5-methyl-2'-O,4'-C-(methylenoxymethylene)cytidine 
• 877823-52-4 4-N-benzoyl-5'-O-(4,4'-dimethoxytrityl)-5-methyl-2'-O,4'-C-(methylenoxymethylene)cytidine 
• 583829-89-4 4-N-benzoyl-3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-2'-O,4'-C-(methylenoxymethylene)cytidine 
• 583829-88-3 4-N-benzoyl-3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-4'-C-hydroxymethyl-cytidine 
• 877823-46-6 4-N-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O,4'-C-(methylenoxymethylene)cytidine 
• 877823-48-8 3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-5-methyl-2'-O,4'-C-(methylenoxymethylene)cytidine 
• 519056-23-6 3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-5-methyl-2'-O,4'-C-(methylenoxymethylene)uridine 
• 519056-22-5 3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-4'-C-hydroxymethyl-5-methyluridine 
• 519056-26-9 5'-O-(4,4'-dimethoxytrityl)-5-methyl-2'-O,4'-C-(methylenoxymethylene)uridine 
• 877823-50-2 4-N-benzoyl-3'-O-benzyl-5-methyl-2'-O,4'-C-(methylenoxymethylene)cytidine 
• 583829-90-7 4-N-benzoyl-3'-O-benzyl-2'-O,4'-C-(methylenoxymethylene)cytidine 
• 877823-51-3 4-N-benzoyl-5-methyl-2'-O,4'-C-(methylenoxymethylene)cytidine 
• 519056-24-7 3'-O-benzyl-5-methyl-2'-O,4'-C-(methylenoxymethylene)uridine 
• 583829-91-8 4-N-benzoyl-2'-O,4'-C-(methylenoxymethylene)cytidine 

Relevant academic research and scientific papers

Synthesis and properties of 2′-O,4′-C-methyleneoxymethylene bridged nucleic acid

A novel bridged nucleic acid (BNA) analogue, 2′-O,4′-C- methyleneoxymethylene bridged nucleic acid (2′,4′-BNA COC), was synthesized and incorporated into oligonucleotides. The 2′,4′-BNACOC modified oligonucleotides showed high bindin