5846-22-0

Basic information

• Product Name: Propanedioic acid, [(3,4-dimethoxyphenyl)methyl]methyl-, dimethyl ester
• CAS NO: 5846-22-0
• Molecular Formula: C15H20O6
• Molecular Weight: 296.32
• Mol File: 5846-22-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, [(3,4-dimethoxyphenyl)methyl]methyl-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, [(3,4-dimethoxyphenyl)methyl]methyl-, dimethyl ester(5846-22-0)
• EPA Substance Registry System: Propanedioic acid, [(3,4-dimethoxyphenyl)methyl]methyl-, dimethyl ester(5846-22-0)

Safety Data

• Hazardous Substances Data: 5846-22-0(Hazardous Substances Data)

Upstream product

• 609-02-9 methyl-malonic acid dimethylester 
• 21852-32-4 4-bromomethyl-1,2-dimethoxybenzene 

Downstream Products

• 39948-18-0 (S)-3-(3,4-dimethoxyphenyl)-2-methylalanine  
• 555-30-6 methyldopa 
• 99531-07-4 (R)-2-(3,4-Dimethoxy-benzyl)-2-methyl-malonic acid monomethyl ester 

Relevant articles and documents

ENZYME CATALYSED HYDROLYSIS OF DIALKYLATED PROPANEDIOIC ACID DIESTERS, SYNTHESIS OF OPTICALLY PURE (S)-α-METHYLPHENYLALANINE, (S)-α-METHYLTYROSINE AND (S)-α-METHYL-3,4-DIHYDROXYPHENYLALANINE

Pig liver esterase and α-chymotrypsin catalysed hydrolysis of the meso-diesters 1, 2 and 3 gave the corresponding monoesters which then could be transformed into enantiomerically pure (S)-α-methylphenylalanine, (S)-α-methyltyrosine and (S)-α-methyl-3,4-dihydroxyphenylalanine.