58475-97-1 Usage
Description
Ethanone, 1-(2-indolizinyl)(9CI) is a heterocyclic aromatic chemical compound with the formula C10H9NO. It features an indolizine ring and is commonly utilized in the pharmaceutical industry as a key building block for synthesizing a variety of biologically active compounds. Its unique structure and properties also make it a promising candidate for applications in organic and medicinal chemistry, as well as a reagent in organic chemical reactions for creating novel compounds. Ethanone, 1-(2-indolizinyl)(9CI) holds potential in the development of innovative drugs and materials.
Uses
Used in Pharmaceutical Industry:
Ethanone, 1-(2-indolizinyl)(9CI) is used as a building block for the synthesis of various biologically active compounds, contributing to the development of new drugs and therapeutic agents.
Used in Organic and Medicinal Chemistry:
Due to its unique structure and properties, Ethanone, 1-(2-indolizinyl)(9CI) is employed in organic and medicinal chemistry for the exploration and creation of new chemical entities with potential applications in various fields.
Used as a Reagent in Organic Chemical Reactions:
Ethanone, 1-(2-indolizinyl)(9CI) serves as a reagent in organic chemical reactions, facilitating the synthesis of novel compounds with potential uses in different industries, including pharmaceuticals, materials science, and more.
Check Digit Verification of cas no
The CAS Registry Mumber 58475-97-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,4,7 and 5 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 58475-97:
(7*5)+(6*8)+(5*4)+(4*7)+(3*5)+(2*9)+(1*7)=171
171 % 10 = 1
So 58475-97-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H9NO/c1-8(12)9-6-10-4-2-3-5-11(10)7-9/h2-7H,1H3
58475-97-1Relevant articles and documents
First example of electrophile induced Baylis-Hillman reaction: A novel facile one-pot synthesis of indolizine derivatives
Basavaiah, Deevi,Rao, Anumolu Jaganmohan
, p. 604 - 605 (2003)
Treatment of pyridine-2-carboxaldehyde with activated alkenes such as alkyl vinyl ketones and cyclic enones in the presence of trimethylsilyl trifluoromethanesulfonate (TMSOTf) provides a novel facile one-pot synthesis of indolizine derivatives, thus for the first time describing an electrophile induced Baylis-Hillman reaction.
Indolizines 3. The synthesis of 2-vinylindolizines and their reaction with dienophiles
Siberdt, F.,Nasielski, J.
, p. 85 - 96 (2007/10/03)
The Wittig olefination of 2-acetylindolizine 2 by methylenetriphenylphosphorane gives 2-isopropenylindolizine 3 with a 99 percent yield; its reaction with dimethyl acetylenedicarboxylate, maleic anhydride, benzoquinone, dimethyl maleate, dimethyl fumarate, N-ethylmaleimide and 4-methyl-1,2,4-triazoline-3,5-dione gives mainly Michael adducts to the available 3 position of the indolizine, and only low amounts of cyclo-addition products.Reaction of 2 with methoxymethylenetriphenylphosphorane gives 54percent of 2-(α-methyl-β-methoxy)vinylindolizine 4; this very electronrich diene undergoes extensive decomposition with most dienophiles; only dimethyl maleate and N-ethylmaleimide gave identifiable products, Michael adducts and cyclo-adducts, and with low yields.
