58479-71-3Relevant articles and documents
Alternative nucleic acid molecules and uses thereof
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, (2015/11/09)
The present disclosure provides alternative nucleosides, nucleotides, and nucleic acids, and methods of using them.
ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF
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, (2016/06/28)
The present disclosure provides alternative nucleosides, nucleotides, and nucleic acids, and methods of using them.
Process for preparing 2-thiouracil nucleosides
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, (2008/06/13)
Some new 1-(2- or 3-deoxy-β-D-pentofuranosyl)-2-thiouracils and 1-β-D-pentofuranosyl-2-thio-6-azauracils have been prepared. Further, it has been found that the known nucleoside compound, 1-β-D-ribofuranosyl-2-thiouracil is active against Herpes virus and against L-1210 leukemia in mice. An improved method of preparing corresponding 2-0-methyluracil and 2-0-methyl-6-azauracil intermediates is described. The method preserves the β-configuration of the starting nucleoside.