5863-63-8Relevant academic research and scientific papers
Method for synthesizing lithocholic acid from deoxycholic acid as raw material
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Paragraph 0044-0047; 0051-0053, (2018/12/13)
The invention belongs to the field of organic chemicals, relates to a method for synthesizing lithocholic acid, and in particular relates to a method for synthesizing lithocholic acid from deoxycholicacid as a raw material. The method comprises the following steps: by taking deoxycholic acid as an initial raw material; carrying out oxidation and a hydrazone generation reaction, and further carrying out a reduction reaction, thereby obtaining the lithocholic acid. The method provided by the invention is low in initial raw material price, easy in raw material obtaining, short in synthesis stepand is a completely novel synthesis route; reagents used in the method are easy to preserve and safe and nontoxic, and the method is gentle in reaction condition, simple in aftertreatment, high in efficiency and total yield and applicable to industrial production.
