58648-64-9

Usage

Uses as a solvent

1,2-Propanediol, 2-(phenylcarbamate) is commonly used as a solvent in various industries due to its ability to dissolve other substances.

Uses as a plasticizer

The compound acts as a plasticizer, which helps to increase the flexibility and durability of plastics by incorporating it into their structure.

Intermediate in chemical manufacturing

1,2-Propanediol, 2-(phenylcarbamate) is used as an intermediate in the production of other chemicals, contributing to the synthesis of various compounds.

Application in coatings, adhesives, and pharmaceuticals

The compound is widely used in the production of coatings, adhesives, and pharmaceuticals due to its versatile properties and low volatility.

Relatively non-toxic

The chemical is considered to be relatively non-toxic, which allows for its use in a variety of applications, including those related to human health and consumption.

Use as an additive in food and personal care products

Due to its safety for human consumption, 1,2-Propanediol, 2-(phenylcarbamate) is used as an additive in food and personal care products.

Potential use in drug delivery systems

The compound has been studied for its potential use in drug delivery systems, as it exhibits biocompatibility and low toxicity, making it a promising candidate for medical applications.

Upstream product

• 57-55-6 propylene glycol 
• 103-71-9 phenyl isocyanate 
• 108-32-7 1,2-propylene cyclic carbonate 
• 62-53-3 aniline 
• 124-38-9 carbon dioxide 
• 75-56-9 methyloxirane 

Relevant academic research and scientific papers

A Metal-Free Synthesis of N-Aryl Carbamates under Ambient Conditions

The first chemo- and site-selective process for the formation of N-aryl-carbamates from cyclic organic carbonates and aromatic amines is reported. The reactions proceed smoothly under extremely mild reaction conditions using TBD (triazabicyclodecene) as an effective and cheap organocatalyst, thus providing a sustainable and new methodology for the formation of a wide variety of useful N-aryl carbamate synthons in good to excellent yields. Computational investigations have been performed and show the underlying reason for the observed unique reactivity as related to an effective proton-relay mechanism mediated by the bicyclic guanidine base. By relay: The previously unknown site-selective attack of arylamines on cyclic carbonates to deliver N-aryl carbamates as the principal product is reported. The organocatalyst TBD guides an effective proton-relay process, thus mediating a chemoselective formation of the carbamate target under extremely mild reaction conditions. The new methodology represents a sustainable, cheap, and attractive process towards these important N-aryl carbamate synthons.

Synthesis of: N -[(2-hydroxyethoxy)carbonyl]glycine from carbon dioxide, ethylene oxide, and α-amino acid by ionic gelation of sodium tripolyphosphate (TPP) and spirulina supported on magnetic KCC-1 in aqueous solution

In this study, a novel ionic gelation (IG) of sodium tripolyphosphate (TPP) and spirulina was prepared that, supported on magnetic fibrous silica nanospheres (Fe3O4/KCC-1/IG), has been developed for the synthesis of N-[(2-hydroxyetho

CO2 activation and fixation: highly efficient syntheses of hydroxy carbamates over Au/Fe2O3

This paper reports an effective route for the syntheses of hydroxy carbamates from the reaction of CO2, epoxides and amines catalyzed by a Au/Fe2O3 catalyst. Under the optimized reaction conditions, various hydroxy carbamates were successfully synthesized with 92-98% isolated yields. The catalyst could be reused for several runs without deactivation. A plausible reaction mechanism was proposed by which the hydroxy carbamate was formed through an ammonium carbamate intermediate and the catalyst mainly promoted further nucleophilic addition between the epoxide and ammonium carbamate.

REGIOSELECTIVE (PHENYLCARBAMOYL)ATION OF POLYHYDROXY COMPOUNDS BY PHENYL ISOCYANATE-ZINC NAPHTENATE

In the presence of zinc naphtenate as the catalyst, the reaction of phenyl isocyanate with 1,2-propanediol and 3,4-isopropylidene-D-mannitol gave the primary phenylcarbamates in high yield. 1,2,6-Hexanetriol was selectively phenylcarbamoylated at O-1 and