58662-78-5

Usage

Structure

Benzoic acid derivative with a benzyl ether substituent at the 4-position and an amino group at the 2-position

Uses

Synthesis of various pharmaceuticals, including NSAIDs and other therapeutic agents

Properties

Potential anti-inflammatory and analgesic properties

Applications

Chemistry, biochemistry, organic synthesis, drug development

Upstream product

• 116027-17-9 2-amino-5-benzyloxybenzoic acid methyl ester 
• 394-31-0 2-amino-5-hydroxybenzoic acid 
• 1882-72-0 methyl 2-amino-5-hydroxybenzoate 
• 154664-44-5 2-acetylamino-5-hydroxybenzoic acid methyl ester 
• 340291-79-4 2-acetylamino-5-benzyloxybenzoic acid methyl ester 

Downstream Products

• 1613722-64-7 3-benzyloxyrutercarpine 
• 1613722-69-2 10-(benzyloxy)-5,6-dihydro-8H-isoquinolino[1,2-b]quinazolin-8-one 
• 344455-10-3 (6-benzyloxy-quinazolin-4-yl)-[2-(4-chloro-phenyl)-ethyl]-amine 
• 1006890-44-3 4-chloro-6-(phenylmethoxy)-quinazoline 
• 929028-80-8 5-benzyloxy-2-[2-(4-benzyl-piperidin-1-yl)-2-oxo-acetylamino]-benzamide 
• 65883-84-3 2-amino-5-(benzyloxy)benzamide 

Relevant academic research and scientific papers

Pyrrolidine(thi)ones Substituted by Heterocyclic Substituents in The 3-Position

Pyrrolidine(thi)one compounds substituted by heterocyclic substituents in the 3-position, their preparation and use in pharmaceutical compositions, in particular as immunomodulators for treatment and/or inhibition of inflammatory and autoimmune diseases and haematological-oncological diseases.

Kynurenic acid amides as novel NR2B selective NMDA receptor antagonists

A novel series of kynurenic acid amides, ring-enlarged derivatives of indole-2-carboxamides, was prepared and identified as in vivo active NR2B subtype selective NMDA receptor antagonists. The synthesis and SAR studies are discussed.

Multisubstituted 1-hydroxy-9-acridones with anticancer activity

The present invention provides a compound having the structure: STR1 The present invention also provides a method for synthesizing a compound having the above-identified structure as well as the intermediate compounds produced according to that method. The present invention further provides a pharmaceutical composition comprising the above compounds. Lastly, the present invention provides a method of inhibiting growth of tumor cells.