5868-03-1

Basic information

• Product Name: (-)-3-(benzyloxy)-4,5-epoxy-14-hydroxy-N-methylmorphinan-6-one
• Synonyms: (-)-3-(benzyloxy)-4,5-epoxy-14-hydroxy-N-methylmorphinan-6-one
• CAS NO: 5868-03-1
• Molecular Weight: 391.467
• Mol File: 5868-03-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (-)-3-(benzyloxy)-4,5-epoxy-14-hydroxy-N-methylmorphinan-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-3-(benzyloxy)-4,5-epoxy-14-hydroxy-N-methylmorphinan-6-one(5868-03-1)
• EPA Substance Registry System: (-)-3-(benzyloxy)-4,5-epoxy-14-hydroxy-N-methylmorphinan-6-one(5868-03-1)

Safety Data

• Hazardous Substances Data: 5868-03-1(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 76-41-5 oxymorphone 

Downstream Products

• 92055-63-5 (-)-3-(benzyloxy)-6,7-didehydro-6,14-dimethoxy-4,5-epoxy-N-methylmorphinan 
• 194468-67-2 7α-spirobenzocyclohexyl-3-O-benzyloxymorphone 
• 194468-68-3 7β-spirobenzocyclohexyl-3-O-benzyloxymorphone 
• 190315-16-3 3-O-benzyl-7-(5',6'-benzo-2'-spiroindanyl)oxymorphone 
• 92055-64-6 O-Benzyl-14-methoxydihydromorphinone 
• 165673-71-2 3-(benzyloxy)-6,7-didehydro-4,5α-epoxy-6,14-diethoxy-N-methylmorphinan 
• 165673-75-6 C₂₉H₃₄ClNO₆ 
• 165673-77-8 3-(benzyloxy)-N-(cyclopropylmethyl)-14-ethoxy-4-methoxymorphinan-6-one 
• 165673-74-5 3-(benzyloxy)-14-ethoxy-4-methoxy-N-methylmorphinan-6-one 
• 165673-72-3 3-(benzyloxy)-4,5α-epoxy-14-ethoxy-N-methylmorphinan-6-one 
• 165673-73-4 3-(benzyloxy)-14-ethoxy-4-hydroxy-N-methylmorphinan-6-one 

Relevant articles and documents

Synthesis and Biological Evaluation of 14-Alkoxymorphinans. 1. Highly Potent Opioid Agonists in the Series of (-)-14-Methoxy-N-methylmorphinan-6-ones

A series of eight (-)-14-methylmorphinan-6-ones was synthesized and biologically evaluated.The morphinanones 3-7 were prepared from 3-desoxy-7,8-dihydro-14-hydroxymorphinone (1).The key step in this synthetic sequence, O-methylation in position 14, was ac