92055-63-5Relevant academic research and scientific papers
Synthesis and Biological Evaluation of 14-Alkoxymorphinans. 1. Highly Potent Opioid Agonists in the Series of (-)-14-Methoxy-N-methylmorphinan-6-ones
Schmidhammer, Helmut,Aeppli, Lislott,Atwell, Louise,Fritsch, Florian,Jacobson, Authur E.,et al.
, p. 1575 - 1579 (2007/10/02)
A series of eight (-)-14-methylmorphinan-6-ones was synthesized and biologically evaluated.The morphinanones 3-7 were prepared from 3-desoxy-7,8-dihydro-14-hydroxymorphinone (1).The key step in this synthetic sequence, O-methylation in position 14, was ac
