58713-33-0

Basic information

• Product Name: 1,3-Dicyclopentylurea
• Synonyms: 1,3-Dicyclopentylurea;N,N'-Dicyclopentylurea
• CAS NO: 58713-33-0
• Molecular Formula: C11H20N2O
• Molecular Weight: 196.2893
• Mol File: 58713-33-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 104-106 °C
• Boiling Point: 381.3±9.0 °C(Predicted)
• Appearance: /
• Density: 1.05±0.1 g/cm3(Predicted)
• PKA: 13.89±0.20(Predicted)
• CAS DataBase Reference: 1,3-Dicyclopentylurea(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dicyclopentylurea(58713-33-0)
• EPA Substance Registry System: 1,3-Dicyclopentylurea(58713-33-0)

Safety Data

• Hazardous Substances Data: 58713-33-0(Hazardous Substances Data)

Usage

Abbreviation

DCPU

Physical state

White, crystalline solid

Solubility

Insoluble in water

Melting point

147-148°C

Primary use

Starting material in the synthesis of pharmaceutical compounds

Applications

Potential anti-cancer and anti-tuberculosis drugs

Additional use

Reagent in organic chemistry reactions

Research potential

Development of new materials and polymers

Molecular structure

Unique, contributing to its properties and applications

Industries

Pharmaceutical and materials science

Upstream product

• 113260-62-1 2,2,2-Trichloro-N-cyclopentyl-acetamide 
• 5070-13-3 bis-(p-nitrophenyl) carbonate 
• 1003-03-8 Cyclopentamine 
• 67-56-1 methanol 
• 124-38-9 carbon dioxide 
• 201230-82-2 carbon monoxide 

Relevant articles and documents

Oxovanadium(v)-catalyzed amination of carbon dioxide under ambient pressure for the synthesis of ureas

Carbon dioxide is regarded as a reliable C1 building block in organic synthesis because of the nontoxic, abundant, and economical characteristics of carbon dioxide. In this manuscript, a commercially available oxovanadium(v) compound was demonstrated to serve as an efficient catalyst for the catalytic amination of carbon dioxide under ambient pressure in the synthesis of ureas. The catalytic transformation of chiral amines into the corresponding chiral ureas without loss of chirality was also performed. Furthermore, a gram-scale catalytic urea synthesis under ambient pressure was successfully achieved to validate the scalability of this catalytic activation of carbon dioxide. This journal is

One-Pot Synthesis of Disubstituted Urea from Carbon Dioxide, Propylene Oxide, and Amines Catalyzed by Imidazolium-Tetraiodoindate

In this article, synthesis of 1,3-disubstituted urea (DSU) from three component reagent systems comprising amine, carbon dioxide, and propylene oxide is described. DSU is synthesized in the presence of a variety of ionic liquids (ILs) with/without promoters. Among used ILs, 1-butyl-3-methylimidazolium tetraiodoindateIII (represented as [Bmim][InI4]) is found to give the highest DSU product. A serious experiment clearly indicates that the tetraiodoindate anion plays an important role for the selective production of the DSU. Based on the in situ infrared spectroscopic studies, a plausible reaction mechanism for producing dicyclohexylurea from cyclohexylamine is proposed. The synthesis and characterization of [Bmim][InI4] are given in details. Moreover, the effect of reaction variables such as time, temperature, pressure, and the molar ratio of substrate to catalyst is also studied.

Ruthenium-Catalyzed Synthesis of Symmetrical N,N'-Dialkylureas Directly from Carbon Dioxide and Amines

Aliphatic and araliphatic primary amines react with carbon dioxide at 120-140 deg C in the presence of ruthenium complexes and terminal alkynes, especilly propargyl alcohols, to directly afford N,N'-disubstituted symmetrical ureas.The alkyne ruthenium intermediate acts as a dehydrating reagent.This new and mild method avoids the classical use of carbonyl precursors like phosgene or isocyanates.