58721-75-8

Usage

Chemical class

Pyrrolidines and quinoline family

Type of compound

Heterocyclic compound

Structure

Contains both a pyrrolidine ring and a quinoline ring

Substituents

Four methyl groups and a trifluoromethyl group attached to the pyrrolidine ring

Molecular structure

Unique and complex

Potential applications

Medicinal chemistry or organic synthesis

Further research

Needed to fully understand its potential uses

Upstream product

• 50-00-0 formaldehyd 
• 207122-73-4 2,3,3-Trimethyl-5-trifluoromethyl-1,2,3,8-tetrahydro-pyrrolo[3,2-g]quinolin-7-one 
• 61360-90-5 6-Amino-1,2,3,3-tetramethylindoline 
• 372-31-6 ethyl 4,4,4-trifluoroacetoacetate 
• 18781-58-3 2,3,3-trimethyl-2,3-dihydro-1H-indole 
• 1640-39-7 2,3,3-trimethylindoleniune 

Relevant academic research and scientific papers

New nonsteroidal androgen receptor modulators based on 4-(trifluoromethyl)-2(1H)-pyrrolidino[3,2-g]quinolinone

A series of 2(1H)-pyrrolidino[3,2-g]quinolinones was prepared and tested for the ability to modulate the transcriptional activity of the human androgen receptor (hAR). The parent compound, 4-(trifluoromethyl)-2(1H)-pyrrolidino[3,2-g]quinolinone, displayed moderate interaction with hAR, but more substituted analogues, particularly 6,7-disubstituted compounds, were potent hAR agonists in vitro.

7-Oxo-1,2,3,3,8-pentamethyl-5-trifluoromethyl-2,3,7,8-tetrahydro-1-H-pyrrolo[3,2-g]q

7-Oxo-1,2,3,3,8-pentamethyl-5-trifluoromethyl-2,3,7,8-tetrahydro-1-H-pyrrol3,2-g] quinoline, a new compound, useful as a blue-green laser dye, is prepared from a substituted indole. It has the expanded formula STR1