58751-62-5Relevant articles and documents
The Heck reaction of allylic alcohols catalysed by an N-heterocyclic carbene-Pd(ii) complex and toxicity of the ligand precursor for the marine benthic copepod: Amphiascoides atopus
Cárdenas, Jorge,Gómez, Samuel,García-Ríos, Eréndira,Gavi?o, Ruben,López-Torres, Adolfo,Morales-Serna, Francisco Neptalí,Morales-Serna, José Antonio,Puello-Cruz, Ana C.,Rios-Ruiz, Lucero
, p. 20278 - 20284 (2021/06/28)
The palladium-catalysed reaction of aryl halides and allylic alcohols is an attractive method for obtaining α,β-unsaturated aldehydes and ketones, which represent key intermediates in organic synthesis. In this context, a 1,2,3-triazol-5-ylidene (aNHC)-based palladium(ii) complex formed in situ has been found to be a selective catalyst for the syntheses of building blocks from the corresponding aryl halides and allylic alcohols, with yields ranging from 50% to 90%. The lack of toxic effects of the ligand precursor (1,2,3-triazolium salt) of the palladium(ii) complex for the harpacticoid copepod Amphiascoides atopus allowed us to contrast the efficiency of the catalytic system with the potential impact of the principal waste chemical in global aquatic ecosystems, which has not been previously addressed.
The Heck reaction of allylic alcohols catalysed by an air-stable phosphinito complex of palladium(II)
Sauza, Alejandro,Morales-Serna, Jose Antonio,Garcia-Molina, Monica,Gavino, Ruben,Cardenas, Jorge
experimental part, p. 272 - 282 (2012/04/17)
The Heck coupling of aryl bromides with primary and secondary allylic alcohols, performed in the presence of an air-stable- phosphinito complex of palladium(II), produced the corresponding carbonyl compounds. Reactions with tertiary allylic alcohols under the same conditions generated the aromatic conjugated alcohols. Georg Thieme Verlag Stuttgart · New York.
Arenediazonium o-benzenedisulfonimides in Heck-type arylation of allylic alcohols
Barbero, Margherita,Cadamuro, Silvano,Dughera, Stefano
, p. 3443 - 3452 (2008/02/12)
Arenediazonium o-benzenedisulfonimides were reacted with primary and secondary allylic alcohols. The reactions, carried out in aqueous ethanol in the presence of palladium(II) acetate as precatalyst and sodium hydrogen carbonate as base, gave the arylation products with good overall conversion. In all cases, the major products were the β-arylated carbonyl derivatives. The o-benzene-disulfonimide was recovered in high yield from all the reactions, and it was recycled for the preparation of other salts. Georg Thieme Verlag Stuttgart.