5877-41-8Relevant articles and documents
Conformational effects on lipase-mediated acylations of 2-substituted cyclohexanols
Tanikaga, Rikuhei,Matsumoto, Yoshimasa,Sakaguchi, Maki,Koyama, Yohei,Ono, Kentaro
, p. 6781 - 6783 (2007/10/03)
Lipase-mediated acetylations of trans- and cis-2-substituted cyclohexanols gave the corresponding (1R)-cyclohexyl acetates and (1S)-cyclohexanols in high yields and ee, but c-4-tert-butyl-c-2-ethenyl-r-1-cyclohexanol was unreactive owing to the steric interaction between the axial OH group and the axial H atoms at the 3- and 5-positions. In the cis-isomer the OH group occupies an equatorial position to bind to the lipase, and less bulky axial alkenyl and alkynyl groups might not so much prevent acetylations than an alkyl group.
Vinyl Cations, 37. Rearrangement of Cyclic Homopropargyl Sulfonates to Condensed Cyclobutanones and Cyclopropyl Ketones
Hanack, Michael,Schuhmacher, Werner,Kunzmann, Erich
, p. 1467 - 1487 (2007/10/02)
Cyclic homopropargyl sulfonates 8 (tosylates, triflates, nonaflates, and damsylates) are prepared and solvolysed.The resulting rearrangement reactions are studied with respect to the properties of the solvents used, leaving groups, the substituent on the triple bond, and with respect to the ring size of the sulfonates 8.
