58774-39-3 Usage
Uses
Used in Organic Synthesis:
(2-Benzylcyclopropyl)benzene is used as a building block in various organic synthesis reactions for the creation of more complex molecules. Its distinct structure and reactivity make it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Production:
In the pharmaceutical industry, (2-benzylcyclopropyl)benzene is used as a key intermediate in the production of drugs. Its unique molecular structure contributes to the development of new medications with potential pharmacological and biological activities.
Used in Agrochemical Development:
(2-Benzylcyclopropyl)benzene also plays a role in the agrochemical sector, where it is utilized as a starting material for the synthesis of pesticides and other agricultural chemicals, helping to improve crop protection and yield.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (2-benzylcyclopropyl)benzene is a subject of interest for drug discovery and development processes. Its distinct structure and reactivity make it an important moiety for designing and creating novel therapeutic agents with potential applications in treating various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 58774-39-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,7,7 and 4 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 58774-39:
(7*5)+(6*8)+(5*7)+(4*7)+(3*4)+(2*3)+(1*9)=173
173 % 10 = 3
So 58774-39-3 is a valid CAS Registry Number.
58774-39-3Relevant academic research and scientific papers
Nondirected, cu-catalyzed sp3 C-H aminations with hydroxylamine-based amination reagents: Catalytic and mechanistic studies
Wang, Anqi,Venditto, Nicholas J.,Darcy, Julia W.,Emmert, Marion H.
, p. 1259 - 1268 (2017/05/29)
This work demonstrates the use of hydroxylamine-based amination reagents RSO2NH-OAc for the nondirected, Cu-catalyzed amination of benzylic C-H bonds. The amination reagents can be prepared on a gram scale, are benchtop stable, and provide benzylic C-H amination products with up to 86% yield. Mechanistic studies of the established reactivity with toluene as substrate reveal a ligand-promoted, Cu-catalyzed mechanism proceeding through Ph-CH2(NTsOAc) as a major intermediate. Stoichiometric reactivity of Ph-CH2(NTsOAc) to produce Ph-CH2-NHTs suggests a two-cycle, radical pathway for C-H amination, in which the decomposition of the employed diimine ligands plays an important role.
The nickel and palladium catalyzed stereoselective cross coupling of cyclopropyl nucleophiles with aryl halides
De Lang,Brandsma
, p. 225 - 232 (2007/10/03)
The reaction of 2-phenylcyclopropylzinc chloride with some substituted (het)aryl halides gave the corresponding coupling products with good yields and stereoselectivities under the influence of a catalytic amount of Pd(PPh3)4. Other Ni- and Pd-catalysts were less efficient. Alkyl-substituted cyclopropyl nucleophiles gave lower yields.
