587832-07-3Relevant articles and documents
Stereospecific synthesis of chiral tertiary alkyl-aryl ethers via Mitsunobu reaction with complete inversion of configuration
Shi, Yao-Jun,Hughes, David L.,McNamara, James M.
, p. 3609 - 3611 (2003)
Mitsunobu reaction of chiral tertiary alcohol (S)-2 with phenol 3 provides the desired ether (R)-1 in moderate yields at elevated temperatures (80-100°C). The SN2 displacement pathway is evident by complete inversion of the (S)-alcohol to (R)-e
Process for the preparation of optically pure isomers of 2-(4-hydroxy phenoxy)-2-methyl-butyric acid methyl ester
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Page/Page column 6, (2008/06/13)
The invention provides a process for preparing R-(+)-2-(4-hydroxyphenoxy)-2-methyl-butyric acid methyl ester of the formula (1): Various embodiments and variants are provided. The invention also provides a process for preparing S-(?)-2-(4-hydroxyphenoxy)-
NOVEL ISOXAZOLE COMPOUNDS HAVING PPAR AGONIST ACTIVITY
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Page/Page column 19, (2010/11/08)
The present invention relates to novel isoxazole compounds of formula (I) having (PPAR) agonist activity, pharmaceutical compositions containing such compounds and methods for their use.