58793-85-4Relevant academic research and scientific papers
Ester-directed orthogonal dual C-H activation and: Ortho aryl C-H alkenylation via distal weak coordination
Agarwal, Vishal,Bakthadoss, Manickam,Reddy, Tadiparthi Thirupathi,Sharada, Duddu S.
supporting information, p. 1406 - 1409 (2022/02/09)
An unprecedented orthogonal cross-coupling between aromatic C(sp2) and aliphatic olefinic C(sp2) carbons of two same molecules via dual C-H bond activation in an intermolecular fashion has been developed using a distal ester-directing group. This new coupling reaction led to the synthesis of the highly functionalized 1,3-diaryl molecular architecture in very good yields and with high chemo- and regioselectivities. In addition, using ester as the distal directing group, ortho C-H olefination of α-methyl aryl acrylates and cinnamic esters with various alkenes has been achieved in very good yields and with a wide range of substrate scope. This journal is
Visible light promoted metal- and photocatalyst-free synthesis of allylarenes
Dossena, Alessandro,Sampaolesi, Susanna,Palmieri, Alessandro,Protti, Stefano,Fagnoni, Maurizio
, p. 10687 - 10692 (2018/03/09)
The metal- and photocatalyst-free synthesis of substituted allylarenes has been carried out under visible light driven conditions. The process was based on the photogeneration of aryl radicals from arylazo sulfones and their ensuing reaction with allyl sulfones. The developed procedure was very efficient when using substrates bearing electron-withdrawing groups, and allowed for the preparation of α-benzyl styrenes and 2-benzyl acrylates in good yields.
Tetraphosphine/palladium-catalyzed Heck reactions of aryl halides with disubstituted alkenes
Kondolff, Isabelle,Doucet, Henri,Santelli, Maurice
, p. 8487 - 8491 (2007/10/03)
cis,cis,cis-1,2,3,4-Tetrakis(diphenylphosphinomethyl)cyclopentane/ [PdCl(C3H5)]2 efficiently catalyses the Heck reaction of disubstituted alkenes such as methyl crotonate, ethyl cinnamate, methyl methacrylate or α-methylstyrene with a variety of aryl halides. In the presence of 1,2-disubstituted alkenes the stereoselectivities of the reactions strongly depend on the substituents of the alkenes. Selectivities up to 97% in favor of E-isomers can be obtained for the addition to methyl crotonate. With the 1,1-disubstituted alkenes methyl methacrylate or α-methylstyrene mixtures of products are obtained.
