588-36-3

Basic information

• Product Name: (4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL
• Synonyms: (4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)ME...;(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL;(4-AMINO-2-METHYLSULFANYL-PYRIMIDIN-5-YL)-METHANOL;4-AMINO-2-METHYLMERCAPTO-PYRIMIDINE-4-CARBINOL;4-AMINO-2-(METHYLTHIO)-5-PYRIMIDINEMETHANOL;4-AMINO-5-HYDROXYMETHYL-2-(METHYLTHIO)PYRIMIDINE;Methioprim;(4-azanyl-2-methylsulfanyl-pyrimidin-5-yl)methanol
• CAS NO: 588-36-3
• Molecular Formula: C₆H₉N₃OS
• Molecular Weight: 171.22
• Product Categories: Amines;Aromatics;Heterocycles;Sulfur & Selenium Compounds
• Mol File: 588-36-3.mol
• Article Data: 33

Chemical Properties

• Melting Point: 126-127°
• Boiling Point: 408.6 °C at 760 mmHg
• Flash Point: 200.9 °C
• Appearance: /
• Density: 1.38 g/cm³
• Vapor Pressure: 2.07E-07mmHg at 25°C
• Refractive Index: 1.646
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 13.08±0.10(Predicted)
• CAS DataBase Reference: (4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL(588-36-3)
• EPA Substance Registry System: (4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL(588-36-3)

Safety Data

• Hazardous Substances Data: 588-36-3(Hazardous Substances Data)

Usage

Chemical Properties

(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL is white cryst powder

Uses

Different sources of media describe the Uses of 588-36-3 differently. You can refer to the following data:
1. Tumor antagonist in mice.
2. (4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL is an intermediate used in the synthesis of Thiamine (T344185). Also, used for the preparation of pyridopyrimidines and naphthyridines as inhibitors of Akt kinase for the treatment of cancer.

InChI:InChI=1/C6H9N3OS/c1-11-6-8-2-4(3-10)5(7)9-6/h2,10H,3H2,1H3,(H2,7,8,9)

Upstream product

• 771-81-3 4-amino-2-(methylthio)pyrimidine-5-carboxylic acid 
• 774-07-2 ethyl 4-amino-2-thioxo-1H-pyrimidine-5-carboxylate 
• 5909-24-0 4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester 
• 776-53-4 ethyl 4-amino-2-methylmercaptopyrimidine-5-carboxylate 

Downstream Products

• 1123-95-1 5-hydroxymethylcytosine 
• 770-31-0 4-amino-2-(methylthio)pyrimidine-5-carbaldehyde 

Relevant articles and documents

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