58851-64-2

Usage

Uses

1. Used in Pharmaceutical Industry:
1a,2,7,7a-Tetrahydro-3,6-diMethoxy-naphth[2,3-b]oxirene is used as a leukotriene inhibitor for its ability to block the action of leukotrienes, which are inflammatory mediators involved in various diseases, including asthma and other respiratory conditions. By inhibiting leukotrienes, 1a,2,7,7a-Tetrahydro-3,6-diMethoxy-naphth[2,3-b]oxirene can help reduce inflammation and alleviate symptoms associated with these conditions.
2. Used in Chemical Research:
1a,2,7,7a-Tetrahydro-3,6-diMethoxy-naphth[2,3-b]oxirene can also be utilized in chemical research as a starting material or intermediate for the synthesis of other complex organic molecules. Its unique structure and functional groups make it a valuable building block for the development of new compounds with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science.
3. Used in Material Science:
Due to its structural features, 1a,2,7,7a-Tetrahydro-3,6-diMethoxy-naphth[2,3-b]oxirene may find applications in the development of novel materials with specific properties, such as improved stability, enhanced reactivity, or unique optical characteristics. These materials could be used in various applications, including coatings, adhesives, or advanced composites.

Upstream product

• 55077-79-7 5,8-dimethoxy-1,4-dihydronaphthalene 
• 6271-40-5 4a,5,8,8a-tetrahydro-1,4-naphthoquinone 
• 3090-45-7 5,8-dihydro-1,4-naphthalenediol 
• 106-51-4 p-benzoquinone 
• 447-53-0 1,2-Dihydronaphthalene 

Downstream Products

• 101333-82-8 (2S,3S)-3-(3,3-Diphenyl-propylamino)-5,8-dimethoxy-1,2,3,4-tetrahydro-naphthalen-2-ol 
• 101333-83-9 (2S,3S)-3-(2,2-Diphenyl-ethylamino)-5,8-dimethoxy-1,2,3,4-tetrahydro-naphthalen-2-ol 
• 101333-89-5 (2S,3S)-3-(4,4-Diphenyl-butylamino)-5,8-dimethoxy-1,2,3,4-tetrahydro-naphthalen-2-ol 
• 101333-87-3 (2S,3S)-3-(3,3-Dicyclohexyl-propylamino)-5,8-dimethoxy-1,2,3,4-tetrahydro-naphthalen-2-ol 
• 101333-96-4 (2S,3S)-3-(5,5-Diphenyl-pentylamino)-5,8-dimethoxy-1,2,3,4-tetrahydro-naphthalen-2-ol 
• 69775-51-5 5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthol 
• 87035-69-6 2,3-bis-(2-hydroxyethyl)-1,4-dimethoxybenzene 
• 64831-71-6 (2S,3S)-3-Cyclohexylamino-5,8-dimethoxy-1,2,3,4-tetrahydro-naphthalen-2-ol 
• 64831-69-2 (2S,3S)-3-(2-Hydroxy-ethylamino)-5,8-dimethoxy-1,2,3,4-tetrahydro-naphthalen-2-ol 
• 64831-72-7 (2S,3S)-3-Benzylamino-5,8-dimethoxy-1,2,3,4-tetrahydro-naphthalen-2-ol 
• 37464-90-7 5,8-dimethoxy-2-tetralone 
• 116584-96-4 6,9-dimethoxy-1-n-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzotrans-quinoxaline 
• 116584-94-2 trans-6,9-dimethoxy-4-n-propyl-2,3,4a,5,10,10a-hexahydro-4H-naphth<2,3-b><1,4>oxazine 
• 116584-95-3 trans-6,9-dimethoxy-4-n-propyl-2,3,4a,5,10,10a-hexahydro-4H-naphtho<2,3-b><1,4>thiazine 

Relevant academic research and scientific papers

Synthesis of anthracyclinone precursor: 5,12-dihydroxy-1,3,4- trihydronaphthacene-2,6,11-quinone

Two practical and efficient approaches for preparing large quantities of 5,12-dihydroxy-1,3,4-trihydronaphthacene-2,6,11-quinone 9 are described. Both synthetic approaches involve a simple route with a fewer number of steps and utilize readily available and inexpensive starting materials. Large-scale production of this precursor may prove to be useful for further research involving the synthesis of antineoplastic anthracyclines and development of their analogs with increased activity and decreased toxicity.

P-aminophenols, derivatives thereof and method of use

p-Aminophenols are provided having the structure STR1 wherein m is 0, 1 or 2; n is 0, 1, 2 or 3; R1 and R2 may be the same or different and are H, hydroxy or alkoxy; R3 is H, lower alkyl, alkanoyl or aroyl and R4 is H, lower alkyl or alkanoyl, and including acid-addition salts thereof. These compounds are useful as inhibitors of leukotriene production and as such are useful as antiallergy, anti-inflammatory and anti-psoriatic agents.

A novel racemization mechanism for the α-hydroxy ketone moiety(C9-position) of optically active anthracyclinone derivatives

The facile acid-catalyzed racemization of optically active anthracyclinone derivatives((S)(+)-1a,b) was found to proceed through the ring-expanded seven-membered α-hydroxyketones(2 and/or 3 for (S)(+)-1a) by subjecting various plausible intermediates to t

5,6,7,8-Tetrahydronaphthalene hypotensive agents

5,6,7,8-Tetrahydronaphthalenes having the structure STR1 and the pharmaceutically acceptable salts thereof, are useful as blood pressure lowering agents. In the above formula R1 can be hydrogen or alkyl; R2 is alkyl; R3 an