588729-96-8

Basic information

• Product Name: Benzamide, N-[[(5-bromo-3-chloro-2-pyridinyl)amino]thioxomethyl]-
• CAS NO: 588729-96-8
• Molecular Formula: C13H9BrClN3OS
• Molecular Weight: 370.657
• Mol File: 588729-96-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzamide, N-[[(5-bromo-3-chloro-2-pyridinyl)amino]thioxomethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-[[(5-bromo-3-chloro-2-pyridinyl)amino]thioxomethyl]-(588729-96-8)
• EPA Substance Registry System: Benzamide, N-[[(5-bromo-3-chloro-2-pyridinyl)amino]thioxomethyl]-(588729-96-8)

Safety Data

• Hazardous Substances Data: 588729-96-8(Hazardous Substances Data)

Upstream product

• 1147550-11-5 ammonium thiocyanate 
• 98-88-4 benzoyl chloride 
• 38185-55-6 5-bromo-3-chloropyridin-2-ylamine 

Downstream Products

• 588730-02-3 N-(6-phenyl-thiazol[5,4-b]pyridin-2-yl)-benzamide 
• 588729-98-0 N-(6-phenyl-thiazolo[4,5-b]pyridin-2-yl)-benzamide 
• 588730-01-2 N-(6-bromo-thiazolo[5,4-b]pyridine-2-yl)-benzamide 
• 588729-97-9 N-(6-bromo[1,3]thiazolo[4,5-b]pyridin-2-yl)benzamide 

Relevant articles and documents

Oxidative cyclization of N-methyl- and N-benzoylpyridylthioureas. Preparation of new thiazolo[4,5-b] and [5,4-b]pyridine derivatives

Cyclization of N-methyl- and N-benzoylpyridylthioureas, prepared from the corresponding aminopyridines, has been realized using various conditions. With bromine in acetic acid or potassium ferricyanide, the cyclization occurred on the nitrogen of the pyridine ring and pyridinium salts or 1,2,4-thiadiazolo[2,3-a]pyridylidene systems were obtained. On the other hand, treatment of the thioureas with sodium methoxide in N-methylpyrrolidinone (NMP) led to formation of thiazolo[4,5-b] and [5,4-b]pyridines, which are interesting targets for biological evaluation.