58876-61-2

Basic information

• Product Name: 2H-1,5-Benzodiazepin-2-one, 1,3-dihydro-1-methyl-4-phenyl-
• Synonyms: 2,3-dihydro-1-methyl-4-phenyl-1H-1,5-benzo-diazepin-2-one;methyl-1 phenyl-4 benzodiazepine-1,5 one-2;1-Methyl-4-phenyl-1,3-dihydro-2H-1,5-benzodiazepin-2-on;1-methyl-4-phenyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one;2H-1,5-Benzodiazepin-2-one,1,3-dihydro-1-methyl-4-phenyl;1-Methyl-4-phenyl,-2,3-dihydro-2-oxo-1,5-benzodiazepine;1,3-dihydro-1-methyl-4-phenyl-(2H)-1,5-benzodiazepin-2-one
• CAS NO: 58876-61-2
• Molecular Formula: C16H14N2O
• Molecular Weight: 250.3
• Mol File: 58876-61-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 69-73 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 460.7±45.0 °C(Predicted)
• Density: 1.15±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 2H-1,5-Benzodiazepin-2-one, 1,3-dihydro-1-methyl-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1,5-Benzodiazepin-2-one, 1,3-dihydro-1-methyl-4-phenyl-(58876-61-2)
• EPA Substance Registry System: 2H-1,5-Benzodiazepin-2-one, 1,3-dihydro-1-methyl-4-phenyl-(58876-61-2)

Safety Data

• Hazardous Substances Data: 58876-61-2(Hazardous Substances Data)

Upstream product

• 115749-31-0 phenyl-3 N-methyl N-(amino-2 phenyl)amino-5 isoxazole 
• 16439-95-5 4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-2-one 
• 74-88-4 methyl iodide 

Downstream Products

• 92868-25-2 1-methyl-3-benzoylquinoxalin-2(1H)-one 
• 58112-92-8 methyl-1 phenyl-4 benzodiazepine-1,5 thione-2 
• 1076-59-1 3-phenyl-4H-isoxazol-5-one 
• 4760-34-3 N-methyl-1,2-phenylenediamine 
• 124411-61-6 1,1-Dichloro-4-methyl-1a-phenyl-1a,2-dihydro-1H,4H-4,8b-diaza-benzo[a]cyclopropa[c]cyclohepten-3-one 

Relevant articles and documents

Synthesis, spectroscopic characterization, X-ray structure, and in vivo neurotropic activity of new 1,5-benzodiazepin-2-ones

The paper reports the synthesis and in vivo pharmacological studies of a series of N-alkyl-1,5-benzodiazepine-2-ones. In this work, 19 novel benzodiazepine derivatives have been prepared and characterized by spectroscopic methods including 2D nuclear magnetic resonance techniques. Crystal structure of 1-benzyl-8-methyl-4-phenyl-1H-benzo[b][1,4]diazepin-2(3H)-one has also been determined by X-ray diffraction. Prediction of activity spectra for substances prediction and docking studies onto human serum albumin were conducted. Two compounds under these investigation showed high antihypoxic, tranquilizing, and anticonvulsant activity in vivo.

Polycyclic α-amino-ε-caprolactams and related compounds

Disclosed are polycyclic α-amino-ε-caprolactams and related compounds which are useful as synthetic intermediates in the preparation of inhibitors of β-amyloid peptide release and/or its synthesis.

SYNTHESIS AND MASS SPECTRA OF 2,3-DIHYDRO-1H-1,5-BENZODIAZEPINE-2-THIONES

2,3-Dihydro-1H-1,5-benzodiazepine-2-thiones and their N-methyl and S-methyl derivatives were synthesized.It was demonstrated by means of the IR, UV, PMR, and mass spectra that in solutions with different polarities 1,5-benzodiazepine-2-thiones exist prima