58928-67-9Relevant academic research and scientific papers
Design and synthesis of 2,3,4,9-tetrahydro-1H-carbazole and 1,2,3,4-tetrahydro-cyclopenta[b]indole derivatives as non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA polymerase
Gopalsamy, Ariamala,Shi, Mengxiao,Ciszewski, Gregory,Park, Kaapjoo,Ellingboe, John W.,Orlowski, Mark,Feld, Boris,Howe, Anita Y. M.
, p. 2532 - 2534 (2007/10/03)
A novel class of HCV NS5B RNA dependent RNA polymerase inhibitors containing 2,3,4,9-tetrahydro-1H-carbazole and 1,2,3,4-tetrahydro-cyclopenta[b] indole scaffolds were designed and synthesized. Optimization of the aromatic region showed preference for 5,8
Tetrahydroquinazolines and dihydrocyclopentapyrimidines as CRF antagonists
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Page/Page column 16, (2010/02/10)
Compounds of the formula (I): and pharmaceutically acceptable salts or prodrugs thereof, wherein m, R1, R2, R3, R4, R5 and R6 are as defined herein. The invention also provides methods for
