94-65-5

Basic information

• Product Name: 2-PROPYLCYCLOHEXANONE
• Synonyms: 2-PROPYLCYCLOHEXANONE;2-propyl-cyclohexanon;2-propylcyclohexan-1-one
• CAS NO: 94-65-5
• Molecular Formula: C₉H₁₆O
• Molecular Weight: 140.22
• EINECS: 202-351-7
• Mol File: 94-65-5.mol
• Article Data: 24

Chemical Properties

• Melting Point: 32.57°C (estimate)
• Boiling Point: 198°C
• Flash Point: 69.2°C
• Appearance: /
• Density: 0,91 g/cm3
• Vapor Pressure: 0.429mmHg at 25°C
• Refractive Index: 1.4510 to 1.4540
• CAS DataBase Reference: 2-PROPYLCYCLOHEXANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PROPYLCYCLOHEXANONE(94-65-5)
• EPA Substance Registry System: 2-PROPYLCYCLOHEXANONE(94-65-5)

Safety Data

• Statements: 10
• Safety Statements: 16
• RIDADR: 1993
• Hazardous Substances Data: 94-65-5(Hazardous Substances Data)

Usage

Uses

2-Propylcyclohexanone is commonly used for chemoselective reactions.

InChI:InChI=1/C9H16O/c1-2-5-8-6-3-4-7-9(8)10/h8H,2-7H2,1H3

Upstream product

• 108-94-1 cyclohexanone 
• 106-94-5 propyl bromide 
• 6279-91-0 ethyl 2-oxo-1-propylcyclohexanecarboxylate 
• 64-17-5 ethanol 
• 60386-53-0 2-propylidenecyclohexanone 
• 1125-99-1 1-(1-Cyclohexen-1-yl)pyrrolidine 
• 107-08-4 1-iodo-propane 
• 92207-92-6 C₁₇H₂₇NO₂S 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 154470-64-1 1-Thia-spiro[4.5]decan-6-one 
• 172288-49-2 cyclohexyl cyclohexenylamine 
• 823-45-0 2-(hydroxymethylene)cyclohexanone 
• 72170-97-9 ((S)-2-Methoxymethyl-pyrrolidin-1-yl)-[2-propyl-cyclohex-(Z)-ylidene]-amine 
• 17851-97-7 1-tri(n-butyl)stannyloxy-1-cyclohexene 

Downstream Products

• 94-65-5 (+)-2-propylcyclohexanone 
• 94-65-5 (-)-2-propylcyclohexanone 
• 1313885-17-4 C₁₁H₁₇ClO₂ 
• 252854-43-6 N-methyl-2-propylcyclohexanamine 
• 36302-45-1 (R)-2-propylcyclohexanone 
• 67113-13-7 (S)-(+)-2-propylcyclohexan-1-one 
• 115510-47-9 7-propyl-2-oxepanone 
• 1239335-05-7 (1R,2S)-4-methoxy-N-(2-propylcyclohexyl)aniline 
• 844695-95-0 trimethyl[(6-propylcyclohex-1-en-1-yl)oxy]silane 
• 91139-47-8 1-Propyl-3-hydroxymethyl-cyclohexanon-⁽²⁾ 
• 62664-67-9 1-Carboxy-2-propylcyclohexan-1-essigsaeure 

Relevant articles and documents

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Base-Free Transfer Hydrogenation of Ketones Using Cp?Ir(pyridinesulfonamide)Cl Precatalysts

N-(2-(Pyridin-2-yl)ethyl)benzenesulfonamide derivatives and 1,1,1-trifluoro-N-(2-(pyridin-2-yl)ethyl)methanesulfonamide (1-4), along with three-legged piano stool Cp?IrIIICl complexes (5-11) (Cp? = pentamethylcyclopentadienyl) bearing pyridinesulfonamide ligands with varying electronic parameters, were synthesized. These ligands and air-stable complexes were characterized by 1H and 13C{1H} NMR spectroscopy, elemental analysis, and single-crystal X-ray diffraction. Precatalysts, 5-11, were assessed for transfer hydrogenation of aryl, diaryl, dialkyl, linear, cycloaliphatic, and α,β-unsaturated ketones, diones, β-ketoesters, and a biomass-derived substrate with 2-propanol, using 1 mol % precatalyst. Catalysis was also efficient using a 0.1 mol % loading. Remarkably, all catalysis experiments can be conducted in air without dried and degassed substrates, and basic additives and halide abstractors are not required for high activity in transfer hydrogenation. Control experiments and a mercury poisoning experiment support a homogeneous catalyzed pathway. Overall, the fastest reactions are observed using electron-poor substrates and precatalysts bearing electron-rich ligands.

TREATMENT FOR ALZHEIMER'S DISEASE AND RELATED CONDITIONS

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