5895-35-2Relevant articles and documents
Total Synthesis of Biselide A, A Cytotoxic Macrolide of Marine Origin
Hayakawa, Ichiro,Okamura, Masami,Suzuki, Kazuaki,Shimanuki, Mami,Kimura, Kizuku,Yamada, Takuya,Ohyoshi, Takayuki,Kigoshi, Hideo
, p. 2958 - 2970 (2017/06/27)
The total synthesis of biselide A based on our earlier strategy of synthesizing haterumalides is reported. The highlights of this approach are the use of regioselective enzymatic hydrolysis for the installation of a C20 oxygen functional group and an asymmetric aldol reaction for the stereoselective introduction of a C3 oxygen functional group.