58979-18-3Relevant academic research and scientific papers
Divergent Coupling of Alcohols and Amines Catalyzed by Isoelectronic Hydride MnIand FeIIPNP Pincer Complexes
Mastalir, Matthias,Glatz, Mathias,Gorgas, Nikolaus,St?ger, Berthold,Pittenauer, Ernst,Allmaier, Günter,Veiros, Luis F.,Kirchner, Karl
supporting information, p. 12316 - 12320 (2016/08/24)
Herein, we describe an efficient coupling of alcohols and amines catalyzed by well-defined isoelectronic hydride MnIand FeIIcomplexes, which are stabilized by a PNP ligand based on the 2,6-diaminopyridine scaffold. This reaction is an environmentally benign process implementing inexpensive, earth-abundant non-precious metal catalysts, and is based on the acceptorless alcohol dehydrogenation concept. A range of alcohols and amines including both aromatic and aliphatic substrates were efficiently converted in good to excellent isolated yields. Although in the case of Mn selectively imines were obtained, with Fe—exclusively monoalkylated amines were formed. These reactions proceed under base-free conditions and required the addition of molecular sieves.
Insight into O2-promoted base-catalyzed N-alkylation of amines with alcohols
Wang, Chao,Chen, Changpeng,Han, Jian,Zhang, Jingyu,Yao, Yingming,Zhao, Yingsheng
supporting information, p. 2972 - 2977 (2015/04/27)
A highly efficient and practical transition-metal-free CsOH/O2 catalyst system was developed for the N-alkylation of amines with alcohols under argon. This strategy was compatible with many alcohols and exhibits excellent functional group tolerance. More significantly, the selective formation of secondary amines was achieved in excellent yields. The detailed mechanistic study gave a clear understanding of the role of base and oxygen in the catalytic cycle.
Selective imine formation from alcohols and amines catalyzed by polymer incarcerated gold/palladium alloy nanoparticles with molecular oxygen as an oxidant
Soule, Jean-Francois,Miyamura, Hiroyuki,Kobayashi, Shu
supporting information, p. 355 - 357 (2013/02/23)
Carbon black stabilized, polymer incarcerated gold/palladium alloy nanoparticles (PICB-Au/Pd) act as an efficient, reusable heterogeneous catalyst for imine synthesis from alcohols and amines through a tandem oxidative process using molecular oxygen as the terminal oxidant.
Novel anti-tuberculosis agents from MCR libraries
Doemling, Alexander,Achatz, Sepp,Beck, Barbara
, p. 5483 - 5486 (2008/02/12)
Structure-based design of libraries of multi-component reaction products yields novel potent anti-tuberculosis compounds. Synthesis and preliminary biological results are presented.
Base induced carbon-nitrogen (C=N) double bond migration in Schiff bases
Gangadasu,Narender,China Raju,Jayathirtha Rao
, p. 2598 - 2600 (2007/10/03)
Various Schiff bases have been prepared to study base induced carbon-nitrogen double bond migrations. Schiff bases derived from aliphatic aldehydes display highest selectivity. Hydrolysis of the resulting rearranged Schiff base provides an entry to make amines from aldehydes. The reaction has possible practical application.
