58981-35-4

Usage

Uses

Used in Pharmaceutical Industry:
2-(4-METHYL-THIAZOL-5-YL)-ETHYLAMINE is used as a synthetic intermediate for the development of various histamine H2 agonists. These agonists have potential applications in the treatment of various medical conditions, such as peptic ulcers, allergies, and other disorders related to the histamine receptor.
Used in Chemical Research:
2-(4-METHYL-THIAZOL-5-YL)-ETHYLAMINE is also utilized in the synthesis of novel compounds for chemical research. Its unique structure allows for the exploration of new chemical reactions and the development of innovative molecules with potential applications in various fields, including pharmaceuticals, materials science, and agrochemicals.

InChI:InChI=1/C6H10N2S/c1-5-6(2-3-7)9-4-8-5/h4H,2-3,7H2,1H3

Upstream product

• 50382-33-7 (4-methyl-1,3-thiazol-5-yl)acetonitrile 
• 854473-13-5 3-(4-methyl-thiazol-5-yl)-propionic acid amide 
• 6508-39-0 3-(4-methyl-thiazol-5-yl)-propionic acid ethyl ester 
• 36956-91-9 4-methyl-5-(β-phthalimidoethyl)thiazole 
• 136384-13-9 (4-methyl-thiazol-5-yl)-acetic acid amide 
• 1759-28-0 4-methyl-5-vinylthiazole 
• 533-45-9 chlormethiazole 
• 406727-23-9 (4-methyl-thiazol-5-yl)-acetic acid ethyl ester 
• 137-00-8 5-hydroxyethyl-4-methylthiazole 
• 122-39-4 diphenylamine 
• 153805-36-8 5-(2-azidoethyl)-4-methylthiazole 

Downstream Products

• 137-00-8 5-hydroxyethyl-4-methylthiazole 
• 153805-39-1 L-idonamide, 6-cyclohexyl-2,5,6-trideoxy-5-amino-2-(1-methylethyl)-N-<2-methyl-1-<<<2-(4-methyl-5-thiazolyl)ethyl>amino>carbonyl>butyl>-, <3aS-<3aα,4β(1R*,2R*),6aα>>- 
• 153805-38-0 carbamic acid, <1-<2,2-dimethyl-5-<2-cyclohexyl-1-<<<2-methyl-1-<<(2-pyridinylmethyl)amino>carbonyl>butyl>amino>carbonyl>ethyl>-1,3-dioxolan-4-yl>-2-methylpropyl>-, 1,1-dimethylethyl ester, <4R-<4α(R*),5β(S*)>> 

Relevant academic research and scientific papers

Direct Access to Primary Amines from Alkenes by Selective Metal-Free Hydroamination

Direct and selective synthesis of primary amines from easily available precursors is attractive yet challenging. Herein, we report the rapid synthesis of primary amines from alkenes via metal-free regioselective hydroamination at room temperature. Ammonium carbonate was used as ammonia surrogate for the first time, allowing for efficient conversion of terminal and internal alkenes into linear, α-branched, and α-tertiary primary amines under mild conditions. This method provides a straightforward and powerful approach to a wide spectrum of advanced, highly functionalized primary amines which are of particular interest in pharmaceutical chemistry and other areas.

Evaluation of a Vitamin-Cloaking Strategy for Oligopeptide Therapeutics: Biotinylated HIV-1 Protease Inhibitors

The outstanding limitations to the oligopeptide as a therapeutic agent are poor oral availability and rapid biliary clearance.To address these concerns a series of eight peptidic HIV-1 protease inhibitors containing the structural segment of the vitamin b