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N6-(1-oxohexadecyl)-L-lysine, also known as C16-lysine, is a lipidated amino acid derivative that is commonly found in lipopeptides and lipoproteins. It contains a long hydrophobic 16-carbon chain attached to the lysine residue and is often used as a lipid anchor for protein modifications, such as palmitoylation. This chemical plays a crucial role in the lipid metabolism of cells and has been implicated in various biological processes, including cell signaling, membrane trafficking, and lipid modification of proteins.

59012-43-0

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59012-43-0 Usage

Uses

Used in Pharmaceutical Industry:
N6-(1-oxohexadecyl)-L-lysine is used as a lipid anchor for protein modifications, such as palmitoylation, for enhancing the stability and function of proteins in drug development.
Used in Biochemical Research:
N6-(1-oxohexadecyl)-L-lysine is used as a platform for the development of antimicrobial peptides, which have potential applications in the treatment of bacterial infections.
Used in Drug Delivery Systems:
N6-(1-oxohexadecyl)-L-lysine is used as a component in the design of drug delivery systems, aiming to improve the targeting and efficacy of therapeutic agents.
Used in Cell Biology Research:
N6-(1-oxohexadecyl)-L-lysine is used as a tool to study the role of lipidation in cell signaling, membrane trafficking, and protein-protein interactions.

Check Digit Verification of cas no

The CAS Registry Mumber 59012-43-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,0,1 and 2 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 59012-43:
(7*5)+(6*9)+(5*0)+(4*1)+(3*2)+(2*4)+(1*3)=110
110 % 10 = 0
So 59012-43-0 is a valid CAS Registry Number.
InChI:InChI=1/C22H44N2O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-18-21(25)24-19-16-15-17-20(23)22(26)27/h20H,2-19,23H2,1H3,(H,24,25)(H,26,27)

59012-43-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-amino-6-(hexadecanoylamino)hexanoic acid

1.2 Other means of identification

Product number -
Other names N6-Palmitoyl-L-lysine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:59012-43-0 SDS

59012-43-0Downstream Products

59012-43-0Relevant academic research and scientific papers

N-heterocyclic amphiphilic amides

-

, (2008/06/13)

The invention relates to novel compounds which are suited for the production of multilayer films which have piezoelectric, and pyroelectric properties, and which provide second harmonic generation. The novel compounds are amphiphilic and it is possible to prepare from same polar single-layer and multi-layer films by depositing them on a substrate. When such substrate is a solid support, polar Z-type Langmuir-Blodgett films are obtained. Upon compression of films of such compounds, at an air/water interface, stable Langmuir monolayers are formed.

HIGHER N-ACYL-L-AMINO ACID DERIVATIVES

Kochetkov, K. A.,Urmambetova, Zh. S.,Belikov, V. M.,Bakasova, Z. B.

, p. 2311 - 2316 (2007/10/02)

A preparative method is proposed for obtaining higher N-acylamino acids by reaction of free amino acids with fatty acid nitrophenyl esters.It was shown that these acids can transport positive ions through a liquid lipophilic medium.A direct method is proposed for obtaining fatty acid 4-nitrophenyl esters by boiling 4-nitrophenol and the fatty acid in xylene in a Soxhlet apparatus in the presence of an acid catalyst.

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