59040-31-2

Upstream product

• 5396-89-4 benzyl acetoacetate 
• 501-53-1 benzyl chloroformate 
• 16466-97-0 1-propynylmagnesium bromide 
• 91285-94-8 O-benzyl S-(pyridin-2-yl)carbonothioate 
• 590-93-2 2-Butynoic acid 
• 100-39-0 benzyl bromide 

Downstream Products

• 145733-71-7 (Z)-3-Acetoxy-but-2-enoic acid benzyl ester 
• 854028-01-6 7-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-1-(4-methoxy-benzylamino)-3-methyl-4a,5,6,7-tetrahydro-pyrrolo[1,2-c]pyrimidine-4-carboxylic acid benzyl ester 
• 854028-02-7 7-(2-hydroxy-ethyl)-1-(4-methoxy-benzylamino)-3-methyl-4a,5,6,7-tetrahydropyrrolo[1,2-c]pyrimidine-4-carboxylic acid benzyl ester 
• 854028-09-4 C₂₉H₂₆NO₂P 
• 854028-10-7 C₂₉H₂₆NO₂P 
• 854028-07-2 (Z)-3-azido-but-2-enoic acid benzyl ester 

Relevant academic research and scientific papers

New alkyne esters and alkyneamide plant antibacterial agents

The present invention relates to a class of propyne esters and propyneamide compounds and synthetic methods thereof, and drugs containing the compound and applications thereof. The two types of compounds have efficient and broad-spectrum inhibitory activity for more than ten kinds of plant pathogenic fungi, and at the same time have the characteristics of simple structure, easy large-scale preparation and high safety of animals and plants, and can be used as active ingredients for the development of new plant antibacterial agents with high efficiency and low toxicity.

Asymmetric Transfer Hydrogenation of gem-Difluorocyclopropenyl Esters: Access to Enantioenriched gem-Difluorocyclopropanes

Catalytic enantioselective access to disubstituted functionalized gem-difluorocyclopropanes, which are emerging fluorinated motifs of interest in medicinal chemistry, was achieved through asymmetric transfer hydrogenation of gem-difluorocyclopropenyl este

Chelation-Based Homologation by Reaction of Organometallic Reagents with O -Alkyl S -Pyridin-2-yl Thiocarbonates: Synthesis of Esters from Grignard Reagents

The one-carbon homologative esterification of Grignard reagents with O- alkyl S -pyridin-2-yl thiocarbonates has been explored. This one-step synthesis of esters from Grignard reagents is the first case to involve chelation-stabilized intermediates.

Facile Dehydration of Activated Ketones to Alkynes

Ketones activated by β-carbonyl or phenyl groups are readily dehydrated to alkynes with (PhP(1+))2O, 2OTf(1-) and triethylamine in refluxing 1,2-dichloroethane.