59046-65-0Relevant academic research and scientific papers
Gold(i)-catalyzed nucleophilic cyclization of β-monosubstituted: O -(alkynyl)styrenes: A combined experimental and computational study
Virumbrales, Cintia,Solas, Marta,Suárez-Pantiga, Samuel,Fernández-Rodríguez, Manuel A.,Marín-Luna, Marta,López, Carlos Silva,Sanz, Roberto
supporting information, p. 9924 - 9932 (2019/12/06)
The stereospecific gold(i)-catalyzed nucleophilic cyclization of β-monosubstituted o-(alkynyl)styrenes to produce C-1 functionalized 1H-indenes including challenging substrates and nucleophiles, such as β-(cyclo)alkyl-substituted o-(alkynyl)styrenes and a variety of alcohols as well as selected electron-rich aromatics, is reported. DFT calculations support the stereochemical outcome of the process that involves the formation of a key cyclopropyl gold carbene intermediate through a regiospecific 5-endo cyclization.
Gold catalysis: Synthesis of 3-acylindenes from 2-alkynylaryl epoxides
Hashmi, A. Stephen K.,Buehrle, Miriam,Salathe, Ralph,Bats, Jan W.
supporting information; experimental part, p. 2059 - 2064 (2009/08/07)
A series of 2-alkynylaryl epoxides were prepared by a sequence of Sonogashira coupling, Wittig olefination and epoxidation or a Darzens' glycid ester synthesis. The conversion of these substrates with gold(I) catalysts furnished 3-acylindenes and, in occa
