59058-19-4Relevant academic research and scientific papers
A simple method for the α-oxygenation of aldehydes
Beshara, Cory S.,Hall, Adrian,Jenkins, Robert L.,Jones, Teyrnon C.,Parry, Rachael T.,Thomas, Stephen P.,Tomkinson, Nicholas C. O.
, p. 1478 - 1480 (2005)
A mild, efficient and general method for the chemospecific α-oxygenation of aldehydes is described. Treatment of a series of aldehydes with N-tert-butyl-O-benzoyl hydroxylamine hydrochloride gives the corresponding α-oxygenated carbonyl via a proposed per
N-Heterocyclic Carbene-Catalyzed Chemoselective Monoacylation of 1, n-Linear Diols
Soeta, Takahiro,Kaneta, Kota,Hatanaka, Yuichi,Ida, Tomonori,Ukaji, Yutaka
supporting information, p. 8138 - 8142 (2021/11/01)
This paper discusses the N-heterocyclic carbene (NHC)-catalyzed redox monoacylation of 1,n-linear diols using α-benzoyloxyaldehydes. The reactions afforded monoacylated diols in moderate to good selectivities and chemical yields. Our original NHC bearing
Practical one-pot sequence for the asymmetric synthesis of 1,2 diols from primary alcohols
Hermange, Philippe,Portalier, Fran?ois,Thomassigny, Christine,Greck, Christine
, p. 1052 - 1055 (2013/04/10)
A practical one-pot three-step sequence is reported for the asymmetric synthesis of α-benzoyloxylated alcohols from primary alcohols. Good overall yields (36-52%) and enantioselectivities (91-94% e.e.) are obtained using a commercial organocatalyst in the key oxylation reaction. A simple modification in the protocol allows the formation of enantioenriched γ-benzoyloxylated α,β-unsaturated ester from alcohol. Synthetic utility has been harnessed to the easy preparation of (-)-γ-octalactone from hexan-1-ol.
METHOD FOR PRODUCING ALPHA-ACYLOXYCARBONYL COMPOUND AND NOVEL ALPHA-ACYLOXYCARBONYL COMPOUND
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Page/Page column 12-13, (2013/02/27)
A method for producing an α-acyloxycarbonyl compound of the present invention includes performing an intermolecular reaction between a carboxylic acid and a carbonyl compound selected from the group consisting of ketones, aldehydes, and esters, which have
In situ generated (Hypo)iodite catalysts for the direct α-oxyacylation of carbonyl compounds with carboxylic acids
Uyanik, Muhammet,Suzuki, Daisuke,Yasui, Takeshi,Ishihara, Kazuaki
supporting information; experimental part, p. 5331 - 5334 (2011/07/08)
It′s the iodine: The intra- and intermolecular title reaction is catalyzed by an in situ generated ammonium (hypo)iodite species. Either H 2O2 or tert-butyl hydroperoxide (TBHP) can be used as an environmentally benign oxidant and a wide range of substrates react to give the corresponding α-acyloxycarbonyl compounds in good to excellent yields.
