5909-46-6

Basic information

• Product Name: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(4-methoxyphenyl)methyl]-
• CAS NO: 5909-46-6
• Molecular Formula: C12H12N2O4
• Molecular Weight: 248.238
• Mol File: 5909-46-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(4-methoxyphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(4-methoxyphenyl)methyl]-(5909-46-6)
• EPA Substance Registry System: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(4-methoxyphenyl)methyl]-(5909-46-6)

Safety Data

• Hazardous Substances Data: 5909-46-6(Hazardous Substances Data)

Usage

General Description

2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(4-methoxyphenyl)methyl]- is a chemical compound with the molecular formula C13H11N3O4. It is an organic compound that belongs to the class of pyrimidine derivatives. This chemical has a pyrimidine ring structure with three nitrogen atoms and is substituted with a methoxyphenylmethyl group at the 5-position. It is used in the pharmaceutical industry as a potential component for drug development, particularly in the field of medicinal chemistry for its potential biological activities. It may also be utilized in scientific research as a reference compound or in chemical synthesis for the production of new compounds.

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 49546-71-6 5-(4-methoxybenzylidene)barbituric acid 

Relevant articles and documents

BARBITURIC ACID DERIVATIVES AS SELF-TANNING SUBSTANCES

The present invention relates to the use of barbituric acid derivatives of the formula I as self-tanning substance, for increasing melanin synthesis, for improving melanin transport and/or improving the distribution of melanin in superbasal layers, to preparations comprising these barbituric acid derivatives, and to specific barbituric acid derivatives.

2-Phenyl-2,3-dihydrobenzo[ d ]thiazole: A Mild, Efficient, and Highly Active in situ Generated Chemoselective Reducing Agent for the One-Pot Synthesis of 5-Monoalkylbarbiturates in Water

A metal- and catalyst-free reductive alkylation protocol for the one-pot synthesis of 5-monoalkylbarbiturates from barbituric acids and aldehydes using the in situ generated chemoselective reducing agent 2-phenyl-2,3-dihydrobenzo[ d ]thiazole from 2-aminothiophenol and benzaldehyde is described. The notable advantages of the protocol are operational simplicity, mild reaction conditions, high yield, short reaction time, and simple workup and purification process which make it highly attractive.

N-HYDROXYLAMINO-BARBITURIC ACID DERIVATIVES AS NITROXYL DONORS

The present disclosure provides N-hydroxylamino-barbituric acid compounds of formulae (1)- (4), pharmaceutical compositions and kits comprising them, and methods of using such compounds or pharmaceutical compositions. The present disclosure provides methods of using such compounds or pharmaceutical compositions for treating heart failure.