59092-97-6

Basic information

• Product Name: 1,3,7-trihydroxy-6-methoxy-9H-xanthen-9-one
• Synonyms: 6-Methoxy-1,3,7-trihydroxyxanthone
• CAS NO: 59092-97-6
• Molecular Formula: C₁₄H₁₀O₆
• Molecular Weight: 274.2256
• Mol File: 59092-97-6.mol

Chemical Properties

• Boiling Point: 588.1°C at 760 mmHg
• Flash Point: 231.1°C
• Density: 1.586g/cm³
• Vapor Pressure: 1.99E-14mmHg at 25°C
• Refractive Index: 1.714
• CAS DataBase Reference: 1,3,7-trihydroxy-6-methoxy-9H-xanthen-9-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,7-trihydroxy-6-methoxy-9H-xanthen-9-one(59092-97-6)
• EPA Substance Registry System: 1,3,7-trihydroxy-6-methoxy-9H-xanthen-9-one(59092-97-6)

Safety Data

• Hazardous Substances Data: 59092-97-6(Hazardous Substances Data)

Usage

Chemical class

Xanthene derivative

Appearance

Bright pink color in acidic form, colorless in basic form

Function

Fluorescent pH indicator

Applications

a. Enzyme assays
b. Cell viability assays
c. Production of fluorescent dyes and pigments

Industrial and research uses

Due to its unique fluorescent properties and ability to provide information about pH levels

Chemical structure

Consists of a xanthene core with three hydroxyl groups (-OH) at positions 1, 3, and 7, a methoxy group (-OCH3) at position 6, and a carbonyl group (C=O) at position 9

Solubility

Generally soluble in organic solvents like ethanol and methanol

Stability

Relatively stable under normal conditions, but sensitive to light and extreme pH levels

Upstream product

• 2237-36-7 4-methoxysalicylic acid 
• 108-73-6 3,5-dihydroxyphenol 
• 5981-37-3 2,5-dihydroxy-4-methoxybenzoic acid 

Downstream Products

• 519-34-6 maclurin 
• 108-73-6 3,5-dihydroxyphenol 
• 3542-72-1 norathyriol 

Relevant articles and documents

BIOSYNTHESIS OF MANGIFERIN IN ANEMARRHENA ASPHODELOIDES BUNGE. II. C-GLUCOSYLATION OF MANGIFERIN

A benzophenone, maclurin-1,3,5-14C3 (3), was efficiently incorporated into C-glucosylxanthones (mangiferin (1) and isomangiferin (2)) of Anemarrhena asphodeloides without randomization, but the labelled aglycone of 1 and 2 (1,3,6,7-tetrahydroxyxanthone-2,4,9a-14C3) (4) was essentially not incorporated.Furthermore, the incorporation of phenylalanine-3-14C into 1 and 2 was clearly suppressed by the addition of non-labelled maclurin (3) to the precursor solution.These results indicate that C-glucosylation of 1 and 2 occurs at the stage of maclurin (3), prior to the formation of the xanthone nucleus, and that 1 and 2 may be biosynthesized via 3-C-glucosylmaclurin (6).A biosynthetic route is proposed for mangiferin (1) and related C-glucosylxanthones.Keywords-Anemarrhena asphodeloides Bunge; biosynthesis; C-glucosylation of xanthone; mangiferin; isomangiferin; maclurin-1,3,5-14C3; 1,3,6,7-tetrahydroxyxanthone-2,4,9a-14C3; phloroglucinol-2,4,6-14C3.