5910-12-3Relevant academic research and scientific papers
2-pyridine substituted urea structural small molecule compounds as well as synthesis and application thereof
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Paragraph 0197; 0829; 0836-0837; 0849-0851, (2020/03/03)
The invention relates to 2-pyridine substituted urea structural small molecule compounds as well as synthesis and application thereof. Specifically, the invention discloses the compounds represented by a formula (I) shown in the specification, enantiomers, diastereomers, racemates or a mixture of the compounds, or a pharmaceutically acceptable salt, hydrate and solvate of the compounds, a preparation method of the above materials, and applications of the above materials in preparation of an ASK1 small molecule inhibitor, or medicines for preventing and/or treating diseases related to ASK1, especially liver diseases, lung diseases, cardiovascular diseases, kidney diseases and metabolic diseases.
Azacycle diketone compound and preparation method thereof (by machine translation)
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Paragraph 0550-0553; 0558-0559, (2020/09/12)
The invention provides a azacyclodiketone compound which is characterized by being a compound represented by the following structure. The compound has inhibitory activity on cap-dependent endonuclease. (by machine translation)
PYRAZOLE DERIVATIVES AS JAK INHIBITORS
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Page/Page column 99, (2011/09/19)
New pyrazole derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).
