59132-97-7

Upstream product

• 23652-90-6 (2Z)-3-amino-1-phenylbut-2-en-1-one 
• 6011-14-9 2-aminoacetonitrile hydrochloride 
• 93-91-4 1-phenylbutan-1,3-dione 
• 540-61-4 2-aminoacetonitrile 

Downstream Products

• 57436-07-4 2-methyl-3-benzoyl-4-aminopyrrole 
• 59133-48-1 (4-amino-2-methyl-1H-pyrrol-3-yl)(phenyl)ketone hydrochloride 
• 131169-20-5 3-Benzoyl-4-benzyl-1-carboxymethyl-2-methyl-7-oxo-4,7-dihydro-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid 
• 131169-19-2 3-Benzoyl-1-carboxymethyl-2-methyl-7-oxo-4-prop-2-ynyl-4,7-dihydro-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid 
• 131169-17-0 3-Benzoyl-1-carboxymethyl-4-ethyl-2-methyl-7-oxo-4,7-dihydro-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid 
• 131169-18-1 4-Allyl-3-benzoyl-1-carboxymethyl-2-methyl-7-oxo-4,7-dihydro-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid 
• 131169-07-8 diethyl N-<1-cyanomethyl-2-methyl-3-benzoylpyrrol-4-yl>aminomethylenemalonate 
• 131169-09-0 1-cyanomethyl-2,4-dimethyl-3-benzoyl-6-carbethoxy-4,7-dihydro-7-oxopyrrolo<3,2-b>pyridine 
• 131169-08-9 1-cyanomethyl-2-methyl-3-benzoyl-6-carbethoxy-7-hydroxypyrrolo<3,2-b>pyridine 
• 131431-74-8 3-Benzoyl-1,2-dimethyl-7-oxo-4-prop-2-ynyl-4,7-dihydro-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid ethyl ester 
• 131169-04-5 2-{[(4-Benzoyl-1,5-dimethyl-1H-pyrrol-3-yl)-methyl-amino]-methylene}-malonic acid diethyl ester 
• 131169-21-6 3-Benzoyl-4-benzyl-1,2-dimethyl-7-oxo-4,7-dihydro-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid 
• 131169-16-9 2,4-dimethyl-3-benzoyl-6-carboxy-4,7-dihydro-7-oxopyrrolo<3,2-b>pyridine-1-acetic acid 
• 131169-11-4 3-Benzoyl-4-ethyl-1,2-dimethyl-7-oxo-4,7-dihydro-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

The synthesis of 5-arylpyrrolo[3,2-b]pyridines and 7-aryl-pyrrolo[3,2-b]pyridines: Addition of 3-aminopyrroles to aryl enaminones

A series of 5-arylpyrrolo[3,2-b]pyridines 1 was synthesized by addition of 3-aminopyrroles to aryl enaminones. One example of a 7-arylpyrrolo[3,2-b]pyridine 2 was obtained as a minor product along with the 5-aryl isomer, by a modification of the reaction sequence.

THE REACTION OF β-AMINOENONES WITH α-AMINO DERIVATIVES. SYNTHESIS OF 2-FUNCTIONALIZED PYRROLES

β-Aminoenones react with ethyl glycinate, α-aminoacetonitrile and α-aminoacetamide hydrochlorides leading to 2-fuctionalized pyrroles.Although the trans-amination is a high-yield process, the transformation of the intermediate, in both basic or thermally