59182-04-6Relevant articles and documents
A tridentate CNO-donor palladium(II) complex as efficient catalyst for direct C―H arylation: Application in preparation of imidazole-based push–pull chromophores
Li, Hui-Hong,Maitra, Ratnava,Kuo, Ya-Ting,Chen, Jie-Hong,Hu, Ching-Han,Lee, Hon Man
, (2017/09/06)
A series of imidazolium chlorides for the formation of tridentate CNO-donor palladium(II) complexes featuring N-heterocyclic carbene moieties have been developed from cheap and readily available starting materials with high yields. Their palladium complex
Ligand-free Pd-catalysed decarboxylative arylation of imidazo[1,2-: A] pyridine-3-carboxylic acids with aryl bromides
Karale, Uttam B.,Kalari, Saradhi,Shivakumar, Jala,Makane, Vitthal B.,Babar, Dattatraya A.,Thakare, Ritesh P.,Babu, Bathini Nagendra,Chopra, Sidharth,Rode, Haridas B.
, p. 65095 - 65104 (2016/07/21)
A facile ligand-free method for Pd(OAc)2 catalysed decarboxylative arylation of imidazo[1,2-a]pyridine-3-carboxylic acids with hetero(aryl) bromides has been developed. This method is applicable to a variety of (hetero)aryl bromides as coupling partners. Electron withdrawing and donating groups on imidazo[1,2-a]pyridine-3-carboxylic acids are well tolerated. It represents the first general protocol for ligand-free Pd(OAc)2 catalysed decarboxylative arylation of imidazo[1,2-a]pyridine-3-carboxylic acids with (hetero)aryl halides. A few of the compounds synthesized using this protocol showed antibacterial activity against Staphylococcus aureus.
Monodentate palladium complexes bearing abnormal and normal carbene ligands with a formally identical steric environment
Ke, Chun-Hung,Kuo, Bing-Chiuan,Nandi, Debkumar,Lee, Hon Man
, p. 4775 - 4784 (2013/09/24)
We report a series of novel isomeric Pd(II) complexes with monodentate abnormal and normal carbene ligands, possessing a formally identical steric environment around the metal center. The corresponding ligand precursors were prepared via the key steps based on Pd-catalyzed direct C-H arylation between imidazo[1,2-a]pyridine and aryl bromides and Cu-catalyzed C-N coupling reactions between benzoimidazole and aryl bromides. The new complexes were characterized by 1D and 2D NMR spectroscopy, X-ray crystallography, and elemental analysis. The isomeric pairs of ligands show minor differences among their steric properties, which were examined by calculating their buried volume. The abnormal carbene Pd(II) complexes were found to be more efficient in catalyzing Mizoroki-Heck coupling, direct C-H arylation, and decarboxylative coupling reactions, which can be clearly attributed to a stronger electronic donating effect of the abnormal carbene ligands.
