59202-80-1Relevant articles and documents
Selection of a synthetic glycan oligomer from a library of DNA-templated fragments against DC-SIGN and inhibition of HIV gp120 binding to dendritic cells
Ciobanu, Mihai,Huang, Kuo-Ting,Daguer, Jean-Pierre,Barluenga, Sofia,Chaloin, Olivier,Schaeffer, Evelyne,Mueller, Christopher G.,Mitchell, Daniel A.,Winssinger, Nicolas
, p. 9321 - 9323 (2011/10/09)
We report the synthesis of a nucleic acid-encoded carbohydrate library, its combinatorial self-assembly into 37485 pairs and a screen against DC-SIGN leading to the identification of consensus ligand motifs. A prototypical example from the selected pairs
Novel cyclic tetraselenides of mannose: synthesis and mechanistic studies
Sivapriya, Kirubakaran,Suguna, Perumal,Chandrasekaran, Srinivasan
, p. 2091 - 2095 (2008/02/04)
In this Letter, we disclose the synthesis of novel cyclic tetraselenides starting from mannose which are very unusual and rare and have been synthesised for the first time. The structures are confirmed by X-ray analysis. The reactivity of the reagent tetr
Synthesis of the bicyclic core of tagetitoxin
Plet, Julien R. H.,Porter, Michael J.
, p. 1197 - 1199 (2008/02/03)
A synthesis of the 9-oxa-3-thiabicyclo[3.3.1]nonane ring system, which constitutes the core of the RNA polymerase inhibitor tagetitoxin, has been achieved through cyclisation of a thiol onto an electrophilic ketone. The Royal Society of Chemistry 2006.
The synthesis of various 1,6-disulfide-B ridged D-hexopyranoses
Goddard-Borger, Ethan D.,Stick, Robert V.
, p. 188 - 198 (2007/10/03)
1,6-Disulfide-bridged derivatives have been prepared for D-gluco-, D-manno-, D-allo-, D-galacto-, and D-talopyranose, in the main by the nucleophilic attack of a C6 thiolate onto an anomeric thiosulfonate. The D-gluco disulfide, 'angyalosan', was successfully oxidized to a single thiosulfinate. CSIRO 2005.
Structure-Activity Relationships of β-D-(2S,5R)- and α-D-(2S,5S)-1,3-oxathiolanyl Nucleosides as Potential Anti-HIV Agents
Jeong, Lak S.,Schinazi, Raymond F.,Beach, J. Warren,Kim, Hea O.,Shanmuganathan, Kirupathevy,et al.
, p. 2627 - 2638 (2007/10/02)
The β-D-(2S,5R)- and α-D-(2S,5S)-1,3-oxathiolanylpyrimidine and -purine nucleosides with natural nucleoside configuration were synthesized and evaluated against HIV-1 in human peripheral blood mononuclear (PBM) cells.The key intermediate 14, which was uti
Enantiomeric Synthesis of (+)-BCH-189 cytosine> from D-Mannose and Its Anti-HIV Activity
Chu, Chung K.,Beach, J. Warren,Jeong, Lak S.,Choi, Bo G.,Comer, Frank I.,et al.
, p. 6503 - 6505 (2007/10/02)
Enantiomerically pure (+)-BCH-189 has been synthesized from D-mannose via 1,6-thioanhydro-D-mannose and its anti-HIV activity has been determined in peripheral blood mononuclear cells.