59202-80-1Relevant articles and documents
Selection of a synthetic glycan oligomer from a library of DNA-templated fragments against DC-SIGN and inhibition of HIV gp120 binding to dendritic cells
Ciobanu, Mihai,Huang, Kuo-Ting,Daguer, Jean-Pierre,Barluenga, Sofia,Chaloin, Olivier,Schaeffer, Evelyne,Mueller, Christopher G.,Mitchell, Daniel A.,Winssinger, Nicolas
supporting information; scheme or table, p. 9321 - 9323 (2011/10/09)
We report the synthesis of a nucleic acid-encoded carbohydrate library, its combinatorial self-assembly into 37485 pairs and a screen against DC-SIGN leading to the identification of consensus ligand motifs. A prototypical example from the selected pairs
Synthesis of the bicyclic core of tagetitoxin
Plet, Julien R. H.,Porter, Michael J.
, p. 1197 - 1199 (2008/02/03)
A synthesis of the 9-oxa-3-thiabicyclo[3.3.1]nonane ring system, which constitutes the core of the RNA polymerase inhibitor tagetitoxin, has been achieved through cyclisation of a thiol onto an electrophilic ketone. The Royal Society of Chemistry 2006.
Structure-Activity Relationships of β-D-(2S,5R)- and α-D-(2S,5S)-1,3-oxathiolanyl Nucleosides as Potential Anti-HIV Agents
Jeong, Lak S.,Schinazi, Raymond F.,Beach, J. Warren,Kim, Hea O.,Shanmuganathan, Kirupathevy,et al.
, p. 2627 - 2638 (2007/10/02)
The β-D-(2S,5R)- and α-D-(2S,5S)-1,3-oxathiolanylpyrimidine and -purine nucleosides with natural nucleoside configuration were synthesized and evaluated against HIV-1 in human peripheral blood mononuclear (PBM) cells.The key intermediate 14, which was uti