59225-86-4

Basic information

• Product Name: 4,7-dimethyl-2H-pyrano[3,2-c]pyridine-2,5(6H)-dione
• Synonyms: 2H-pyrano[3,2-c]pyridine-2,5(6H)-dione, 4,7-dimethyl-; 4,7-Dimethyl-2H-pyrano[3,2-c]pyridine-2,5(6H)-dione
• CAS NO: 59225-86-4
• Molecular Formula: C₁₀H₉NO₃
• Molecular Weight: 191.1834
• Mol File: 59225-86-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 431.9°C at 760 mmHg
• Flash Point: 215°C
• Density: 1.32g/cm³
• Vapor Pressure: 1.15E-07mmHg at 25°C
• Refractive Index: 1.59
• CAS DataBase Reference: 4,7-dimethyl-2H-pyrano[3,2-c]pyridine-2,5(6H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 4,7-dimethyl-2H-pyrano[3,2-c]pyridine-2,5(6H)-dione(59225-86-4)
• EPA Substance Registry System: 4,7-dimethyl-2H-pyrano[3,2-c]pyridine-2,5(6H)-dione(59225-86-4)

Safety Data

• Hazardous Substances Data: 59225-86-4(Hazardous Substances Data)

Upstream product

• 105-53-3 diethyl malonate 
• 3950-10-5 5-Ethoxycarbonyl-4-hydroxy-6-methyl-pyridin-2(1H)-on 
• 14205-39-1 methyl (E)-3-aminocrotonate 
• 3749-51-7 4-hydroxy-6-methyl-2-pyridone 
• 35287-60-6 4,7-dimethyl-2,5-dioxo-5,6-dihydro-2H-pyrano[3,2-c]pyridine-8-carboxylic acid ethyl ester 
• 626-34-6 ethyl aminocrotonate 
• 141-97-9 ethyl acetoacetate 
• 6864-62-6 phenyl acetoacetate 

Relevant articles and documents

Synthesis of some substituted 2H-pyrano[3,2-c] pyridine-2,5(6H)-diones. Reaction of their 3-acetyl derivatives with methyl 3-amino-2-butenoate

Formylation of 4-hydroxy-6-methyl-2(1H)-pyridones and subsequent cyclization with a Wittig reagent or with CH-acidic esters gave a series of title compounds. The same starting pyridones reacted with methyl 3-amino-2- butenoate directly to the corresponding 4,7-dimethylpyrano[3,2-c]pyridines.