59236-38-3

Basic information

• Product Name: 2-AMINO-4-METHYLBENZALDEHYDE
• Synonyms: 2-AMINO-4-METHYLBENZALDEHYDE
• CAS NO: 59236-38-3
• Molecular Formula: C₈H₉NO
• Molecular Weight: 135.16
• Mol File: 59236-38-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 271.0±28.0 °C(Predicted)
• Appearance: /
• Density: 1.129±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 0.48±0.10(Predicted)
• CAS DataBase Reference: 2-AMINO-4-METHYLBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4-METHYLBENZALDEHYDE(59236-38-3)
• EPA Substance Registry System: 2-AMINO-4-METHYLBENZALDEHYDE(59236-38-3)

Safety Data

• Hazardous Substances Data: 59236-38-3(Hazardous Substances Data)

Usage

General Description

2-AMINO-4-METHYLBENZALDEHYDE is a chemical compound with the molecular formula C8H9NO. It is a light yellow solid with a molecular weight of 135.16 g/mol. 2-AMINO-4-METHYLBENZALDEHYDE is an important intermediate in the synthesis of various pharmaceuticals, dyes, and organic compounds. It is commonly used in organic synthesis and chemical research due to its versatile reactivity and wide range of applications. 2-AMINO-4-METHYLBENZALDEHYDE has a strong odor and should be handled with care, as it may cause irritation to the eyes, skin, and respiratory tract. Overall, this compound plays a crucial role in the production of numerous important chemicals and materials used in various industries.

Upstream product

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Relevant articles and documents

Cationic Iridium-Catalyzed Asymmetric Decarbonylative Aryl Addition of Aromatic Aldehydes to Bicyclic Alkenes

We report an unprecedented catalytic protocol for the enantioselective decarbonylative transformation of aryl aldehydes. In this process, the decarbonylation of aldehydes catalyzed by chiral iridium complexes enabled the formation of asymmetric C?C bonds

Easy Access to Quinolin-2(1 H)-ones via a One-Pot Tandem Oxa-Michael-Aldol Sequence

An efficient strategy for the synthesis of a variety of quinolin-2(1 H)-one derivatives has been developed. The reaction proceeded from cinnamide derivatives via a tandem reaction in the presence of NaOH to afford the corresponding 2- quinolin-2(1 H)-one derivatives in good to excellent yields.

Plant antitumor agents. 25. Total synthesis and antileukemic activity of ring a substituted camptothecin analogues. Structure-activity correlations

Nineteen racemic ring A substituted analogues of the antitumor agent 20(S)-camptothecin were prepared by total synthesis and evaluated for in vitro cytotoxic activity against KB cell culture and in vivo antileukemic activity against L1210. These compounds bore a wide variety of substitutents at C11 designed to confer upon the ring system a broad range of combinations of electronic, steric, and lipophilic effects. A few C10-substituted derivatives as well as C10,C11-disubstituted analogues prepared as part of a concurrent study have also been included for general comparison. With the notable exception of the cyano derivative, the 11-substituted compounds displayed only modest in vitro and in vivo activities, and there was a remarkable insensitivity toward the nature of the substituent. In contrast, the 9- and 10-substituted compounds exhibited a considerably higher level of dose potency and activity both in vitro and in vitro.