Cas 592479-28-2,4-(2-benzyloxy-5-chloro-phenyl)-3-(2-hydroxy-ethyl)-6-trifluoromethyl-1<i>H</i>-quinolin-2-one

592479-28-2

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Basic information

Product Name: 4-(2-benzyloxy-5-chloro-phenyl)-3-(2-hydroxy-ethyl)-6-trifluoromethyl-1H-quinolin-2-one
Synonyms: 4-(2-benzyloxy-5-chloro-phenyl)-3-(2-hydroxy-ethyl)-6-trifluoromethyl-1H-quinolin-2-one
CAS NO:592479-28-2
Molecular Formula:
Molecular Weight: 473.879
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 4-(2-benzyloxy-5-chloro-phenyl)-3-(2-hydroxy-ethyl)-6-trifluoromethyl-1H-quinolin-2-one(CAS DataBase Reference)
NIST Chemistry Reference: 4-(2-benzyloxy-5-chloro-phenyl)-3-(2-hydroxy-ethyl)-6-trifluoromethyl-1H-quinolin-2-one(592479-28-2)
EPA Substance Registry System: 4-(2-benzyloxy-5-chloro-phenyl)-3-(2-hydroxy-ethyl)-6-trifluoromethyl-1H-quinolin-2-one(592479-28-2)

Safety Data

Hazard Codes: N/A
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Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 592479-28-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 592479-28-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,9,2,4,7 and 9 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 592479-28:
(8*5)+(7*9)+(6*2)+(5*4)+(4*7)+(3*9)+(2*2)+(1*8)=202
202 % 10 = 2
So 592479-28-2 is a valid CAS Registry Number.

592479-28-2Upstream product

96-48-0 4-butanolide

592479-28-2Downstream Products

275375-69-4 4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)-2(1H)-quinolinone

592479-28-2Relevant academic research and scientific papers

A mild and efficient synthesis of 4-aryl-quinolin-2(1H)-ones via a tandem amidation/Knoevenagel condensation of 2-amino-benzophenones with esters or lactones

Wang, Jianji,Discordia, Robert P.,Crispino, Gerard A.,Li, Jun,Grosso, John A.,Polniaszek, Richard,Truc, Vu C.

, p. 4271 - 4273 (2003)

Using LiHMDS as the base, a tandem amidation/Knoevenagel condensation of 2-aminobenzophenones with α-methylene esters or lactones gives 4-aryl-quinolin-2(1H)-ones in 65-96% yield. This method is mild, highly efficient, and amenable to scaleup.

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