5925-53-1

Basic information

• Product Name: (4Z)-2-(1,3-benzothiazol-2-yl)-4-{1-[(4-methylpiperazin-1-yl)amino]ethylidene}-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one
• CAS NO: 5925-53-1
• Molecular Formula: C₁₃H₁₈N₂OS
• Molecular Weight: 424.4433
• Mol File: 5925-53-1.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 441.7°C at 760 mmHg
• Flash Point: 220.9°C
• Density: 1.52g/cm³
• Vapor Pressure: 5.33E-08mmHg at 25°C
• Refractive Index: 1.675
• CAS DataBase Reference: (4Z)-2-(1,3-benzothiazol-2-yl)-4-{1-[(4-methylpiperazin-1-yl)amino]ethylidene}-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4Z)-2-(1,3-benzothiazol-2-yl)-4-{1-[(4-methylpiperazin-1-yl)amino]ethylidene}-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one(5925-53-1)
• EPA Substance Registry System: (4Z)-2-(1,3-benzothiazol-2-yl)-4-{1-[(4-methylpiperazin-1-yl)amino]ethylidene}-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one(5925-53-1)

Safety Data

• Hazardous Substances Data: 5925-53-1(Hazardous Substances Data)

Upstream product

• 1696-20-4 4-acetylmorpholine 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 4394-85-8 4-morpholinecarboxaldehyde 
• 162274-53-5 4-<(Diphenylphosphinoyl)(4-(dimethylamino)phenyl)methyl>morpholine 
• 110-91-8 morpholine 
• 889-37-2 N,N-dimethyl-4-((phenylimino)methyl)aniline 

Downstream Products

• 1314692-79-9 C₁₁H₁₃NO₃S 
• 118792-43-1 S-methyl 4-(dimethylamino)benzothioate 
• 1215310-00-1 C₁₄H₂₁NOS 
• 1215309-90-2 S-benzyl 4-(dimethylamino)benzothioate 
• 31646-11-4 4-<4-(Dimethylamino)selenobenzoyl>morpholine 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 120290-15-5 Dimethyl-[4-(methylsulfanyl-morpholin-4-yl-methyl)-phenyl]-amine 
• 1874-35-7 2-(N,N-dimethyl-4-aminophenyl)-5-phenyl-1,3,4-oxadiazole 
• 111997-60-5 2-(2-hydroxyphenyl)-5-(4-dimethylaminophenyl)-1,3,4-oxadiazole 
• 111997-61-6 2-(4-pyridyl)-5-(p-dimethylamino)phenyl-1,3,4-oxadiazole 
• 84302-62-5 2-(4-Dimethylamino-phenyl)-4-(4-methoxy-phenyl)-thiazole-5-carbonitrile 
• 84302-60-3 4-(4-Chloro-phenyl)-2-(4-dimethylamino-phenyl)-thiazole-5-carbonitrile 
• 84302-61-4 2-(4-Dimethylamino-phenyl)-4-p-tolyl-thiazole-5-carbonitrile 
• 84302-59-0 2-(4-Dimethylamino-phenyl)-4-phenyl-thiazole-5-carbonitrile 

Relevant articles and documents

Mixed bases mediated synthesis of thioamides in water

A mixed bases mediated protocol is developed to synthesize thioamides from N-aryl or N-alkylamide, aldehyde and elemental sulfur in water. This reaction requires no addition of external oxidant and avoids large excess of amides. Various functional groups

Zinc chloride catalyzed ring opening of N-arylsulfonyl aziridines by thioamides: A new approach to the synthesis of amidines

The first zinc chloride catalyzed ring opening of N-arylsulfonyl aziridines by thioamides is described. Various thioamides were reacted with N-arylsulfonyl aziridines in the presence of a catalytic amount of dry zinc chloride to provide the corresponding

Highly efficient synthesis of thioesters in water

Thioesters were efficiently prepared via the direct reaction of tertiary thioamides and alkyl halides in water, and in the presence of catalytic amounts of NaI, hexadecyltrimethylammonium bromide (HTAB), and 1,4-diazabicyclo[2.2.2] octane (DABCO). Hence,