5927-57-1Relevant academic research and scientific papers
Cyanine type modified compound Intermediate and preparation method and application thereof
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Paragraph 0046-0048, (2021/11/03)
The invention provides a cyanine type modified compound with the structure of the formula (I), and also provides a preparation method of the cyanine type modified compound. The Vinamidinium-salt new synthetic route is developed, the process parameters are optimized, the yield of the intermediate is improved, the product quality is also good, and the effect of increasing the yield of the next step is crucial. In addition, since the cyanine-based modified compound contains more double bonds and strong electron-withdrawing groups, it can be used as an ultraviolet - blue light absorbent.
Synthesis and physico-chemical properties of ionic liquids—3-methyl-1-alkyloxycarbonylmethylpyridinium hexafluorophosphates
Zhuravlev,Voronchikhina
, p. 940 - 944 (2017/06/28)
Ionic liquids based on 1-alkyloxycarbonylmethyl-3-methylpyridinium and Cl– and PF6 – anions have been synthesized. The conductivity of their solutions in acetonitrile and the thermal stability over 25–500°C in air have been determined.
Soft antimicrobial agents: Synthesis and activity of labile environmentally friendly long chain quaternary ammonium compounds
Thorsteinsson, Thorsteinn,Másson, Már,Kristinsson, Karl G.,Hjálmarsdóttir, Martha A.,Hilmarsson, Hilmar,Loftsson, Thorsteinn
, p. 4173 - 4181 (2007/10/03)
A series of soft quaternary ammonium antimicrobial agents, which are analogues to currently used quaternary ammonium preservatives such as cetyl pyridinium chloride and benzalkonium chloride, were synthesized. These soft analogues consist of long alkyl chain connected to a polar headgroup via chemically labile spacer group. They are characterized by facile nonenzymatic and enzymatic degradation to form their original nontoxic building blocks. However, their chemical stability has to be adequate in order for them to have antimicrobial effects. Stability studies and antibacterial and antiviral activity measurements revealed relationship between activity, lipophilicity, and stability. Their minimum inhibitory concentration (MIC) was as low as 1 μg/mL, and their viral reduction was in some cases greater than 6.7 log. The structure-activity studies demonstrate that the bioactive compounds (i.e., MIC for Gram-positive bacteria of 10μg/mL) have an alkyl chain length between 12 and 18 carbon atoms, with a polar headgroup preferably of a small quaternary ammonium group, and their acquired inactivation half-life must be greater than 3 h at 60 °C.
Micellar properties of sodium alkyl sulfoacetates and sodium dialkyl sulfosuccinates in water
Jobe, David J.,Reinsborough, Vincent C.
, p. 280 - 284 (2007/10/02)
Viscosity, conductivity, density, and fluorescence quenching studies were conducted in aqueous micellar solutions at 25.0 deg C of sodium alkyl sulfoacetates and sodium dialkyl sulfosuccinates in a comparison of one-tailed and two-tailed surfactant systems.The hexyl, octyl, and decyl members of the former group and the dihexyl and dioctyl members of the latter group were investigated.The results indicated that the sulfoacetates most likely form spherical micelles with aggregation numbers 20 for hexyl, 42 for octyl, and 70 for decyl with three methods for size determination giving concordant results.For the sulfosuccinates, the aggregation numbers from fluorescence quenching were 38 for the dihexyl and 56 for the dioctyl in agreement with the results from the conductance technique which means that spherical micelles are likely formed also.Volume changes on micellization were obtained for the sulfoacetates.
