59277-55-3

Upstream product

• 98-52-2 4-(1,1-dimethylethyl)-cyclohexanol 
• 108-98-5 thiophenol 
• 7453-04-5 cis-4-tert-butylcyclohexyl tosylate 
• 937-05-3 cis-4-tert-butyl-1-cyclohexanol 
• 18508-90-2 trans-4-tert-butylmesyloxycyclohexane 
• 21862-63-5 trans-4-tert-butylcyclohexanol 
• 7453-05-6 toluene-4-sulfonic acid-(trans-4-tert-butyl-cyclohexyl ester) 
• 930-69-8 sodium thiophenolate 

Downstream Products

• 2455-13-2 cis-4-tert-butylcyclohexyl phenyl sulphoxide 
• 97634-88-3 cis-4-(t-butyl)-1-(phenylsulfonyl)cyclohexane 

Relevant academic research and scientific papers

CsF in organic synthesis. Inversion of secondary mesylates and tosylates

Clean inversion of secondary mesylates and tosylates is effected by CsF in DMF. A variety of oxygen-, sulfur-, nitrogen-, and carbon-nucleophiles are employable. The reaction conditions have been optimized. The use of CsF in DMF is crucial and the reaction proceeds on the surface of solid CsF. It is suggested that hydrogen bonding between CsF and an active hydrogen of nucleophiles is responsible for the smooth reaction. Cesium carbonate fails to give rise to high specificity of inversion indicative of superiority of CsF.

Stereoselective Protonation of Carbanions, 1. - Diastereoselective Protonation of C-H-Activated Cyclohexane Derivatives

The diastereoselectivity of the kinetically controlled protonation of carbanions derived from 4-tert-butyl-1-X-cyclohexanes (1: X = CN, 2: X = CO2Me, 2-Si: X = C(OMe)OSiMe3, 3: X = COPh, 4: X = SO2Ph) is systematically investigated.By variation of (a) the