593-88-4

Usage

Uses

Used in Environmental Research:
Trimethylarsine is used as a subject of study in environmental research for understanding its presence in lake sediments and the impact it has on the ecosystem. Researchers investigate the sources, distribution, and potential risks associated with this pollutant to develop strategies for mitigating its harmful effects.
Used in Toxicology Studies:
Trimethylarsine is utilized as a test compound in toxicology studies to evaluate its toxic effects on mammalian cells. These studies help in understanding the mechanisms of toxicity, identifying potential health risks, and developing methods for detoxification or treatment in cases of exposure.
Used in Chemical Synthesis:
Although primarily recognized as a pollutant, trimethylarsine may also have potential applications in chemical synthesis. Its unique structure and reactivity could be harnessed for the development of new compounds or materials with specific properties, although this application would require careful consideration of its toxic nature and environmental impact.

InChI:InChI=1/C3H9As/c1-4(2)3/h1-3H3

Upstream product

• 67-56-1 methanol 
• 917-64-6 methyl magnesium iodide 
• 676-75-5 dimethyliodoarsine 
• 861587-66-8 2-arsono-propionic acid 
• 471-35-2 tetramethyldiarsine 
• 503-80-0 bis-{dimethylarsenic}-oxide 
• 75-60-5 Dimethylarsinic acid 
• 107-38-0 arsonoacetic acid 
• 544-97-8 dimethyl zinc(II) 
• 127-08-2 potassium acetate 
• 18430-79-0 trimethyl-arsine oxide; nitrate 
• 5967-62-4 methyl-arsonic acid ; disodium salt 
• 5814-20-0 tetramethylarsonium iodide 
• 74-88-4 methyl iodide 

Downstream Products

• 64049-02-1 iodomethyl-trimethyl-arsonium; iodide 
• 71802-31-8 2-Hydroxyethyltrimethylarsoniumbromid 
• 2229-07-4 methyl radical 
• 74-84-0 ethane 
• 83636-34-4 di-methyl arsenic 
• 83636-33-3 monomethyl arsenic 
• 187737-37-7 propene 
• 34557-54-5 methane 
• 74-98-6 propane 
• 74-85-1 ethene 
• 41262-21-9 Trimethyl-arsinselenid 
• 4964-14-1 trimethylarsine oxide 
• 85040-50-2 fac-tricarbonyl-η3-((EE)-2-penten-4-yl)-trimethylarsine-manganese 
• 85040-33-1 cis-benzyltetracarbonyl-trimethylarsine-manganese 

Relevant academic research and scientific papers

Highly efficient synthesis of trimethylarsine

A convenient, highly efficient, and environmentally safe procedure for the preparation of trimethylarsine was proposed. A quantitative yield of this compound in the reaction of As2O3 with AlMe3 was attained for the first time by using mechanochemical activation of the process.

Synthesis of trimethylated phosphonium and arsonium analogues of the osmoprotectant glycine betaine; contrasted biological activities in two bacterial species

Phosphoniobetaine and arsenobetaine, the P and As analogues of glycine betaine (trimethylammonioacetate) were synthesized and assayed for activity in bacterial osmoprotection biotests, using Escherichia coli and Rhizobium meliloti as model organisms. The P- and As-betaines displayed similar osmoprotective activities in E. coli, but were highly toxic in the betaine- demethylating bacterium R. meliloti.

Synthesis of a Homologous Series of Trialkyl Arsines (C3-C12) and Applications of Arsenic Triiodide as a Synthetic Precursor

This work presents some modifications in the post-synthetic processing for a classical arsenic reagent: AsI3. In comparison with the widely used analog, the trichloride, arsenic triiodide presents several advantages such as low toxicity, air stability, and low volatility. It was used as a synthetic precursor in the preparation of a variety of arsenic(III) derivatives like arsines, arsenites, and thioarsenites. Besides that, AsI3 was submitted to a diversity-oriented Grignard reaction in the preparation of a homologous series of trialkyl arsines ranging from AsC3H9 to AsC12H27. The series was analyzed by comprehensive two-dimensional gas chromatography coupled with time-of-flight mass spectrometry to provide a trialkyl arsines library that can be used for the direct analysis of natural samples.

Demethylation of Methylated Arsenic Species during Generation of Arsanes with Tetrahydridoborate(1-) in Acidic Media

Demethylation during generation of volatile hydrides (HG), i.e. formation of noncorresponding arsanes from monomethylarsonic acid (MAsV), dimethylarsinic acid (DMAsV), and trimethylarsine oxide (TMAsVO) by the reaction of

Trialkyl Group VA metal compounds

Disclosed are methods of preparing trialkyl Group VA metal compounds in high yield and high purity. Such trialkyl Group VA metal compounds are substantially free of oxygenated impurities, ethereal solvents and metallic impurities.

Synthesis of Trimethylarsenic

Simple and convenient procedure for preparing trimethylarsenic in the yield exceeding 90% by reaction of As2O3 with Me3Al was proposed.

Metal alkyl process

Metal alkyls such as trimethyl arsine are made in improved yields by reacting a metal halide, e.g. AsCl3, with a Grignard reagent such as methyl magnesium bromide complexed with a polyether such as di(2-methoxyethyl)ether.

Isolation, Crystal Structure and Synthesis of Arsenobetaine, a Constituent of the Western Rock Lobster, the Dusky Shark, and Some Samples of Human Urine

Arsenobetaine has been isolated from the tail muscle of the western rock lobster (Panulirus cygnus George) and from the flesh of the dusky shark (Carcharhinus obscurus Le Sueur), both of which are commercially important seafoods.Trigonelline has also been isolated from the lobster and both arsenobetaine and trigonelline have been isolated from human urine obtained after ingestion of cooked rock lobster. The crystal structures of the monohydrates of arsenobetaine and trigonelline have been determined and a simple synthesis of arsenobetainehas been developed.